SCHEMBL14615433

SCHEMBL14615433

C=Cc1cc(P(=O)(c2cc(C(C)(C)C)c(OC)c(C(C)(C)C)c2)C(C)C(C)P(=O)(c2cc(C(=C)C)c(OC)c(C(C)(C)C)c2)c2cc(C(=C)C)c(OC)c(C(C)(C)C)c2)cc(C(C)(C)C)c1OC

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RARG P13631 1/20 0.33
RXRA P19793 1/20 0.33
PPARG P37231 1/20 0.33
TNFRSF1A P19438 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14045908 0.91 TNFRSF1A (0.34) RARGRXRAPPARGTNFRSF1A
SCHEMBL12585362 0.91 TNFRSF1A (0.34) RARGRXRAPPARGTNFRSF1A
SCHEMBL14026094 0.78 PTGS2 (0.38) TNFRSF1A
SCHEMBL18465077 0.66 CYP1A2 (0.35) TNFRSF1A
SCHEMBL470720 0.66 TNFRSF1A (0.33) RARGRXRAPPARGTNFRSF1A
SCHEMBL13705717 0.66 RXRA (0.50) RARGRXRAPPARGTNFRSF1A
SCHEMBL8302162 0.64 TNFRSF1A (0.47) RARGRXRAPPARGTNFRSF1A
SCHEMBL18634582 0.64 RXRA (0.42) RARGRXRAPPARGTNFRSF1A
SCHEMBL18465076 0.64 ALDH1A1 (0.39) RARGRXRAPPARGTNFRSF1A
SCHEMBL8308995 0.63 TNFRSF1A (0.43) RARGRXRAPPARGTNFRSF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007012655-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE DIPHOSPHANES BASF SE (DE) 2007-02-01 WO disclosed