Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 10/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4710553 | 0.88 | CNR1 (0.33) | KMT2ANPC1RAB9ANR3C1CNR1 | |
| SCHEMBL4711808 | 0.81 | NR3C1 (0.33) | NR3C1CNR1 | |
| SCHEMBL4124704 | 0.80 | DGAT2 (0.47) | — | |
| SCHEMBL4121556 | 0.80 | DGAT2 (0.47) | — | |
| SCHEMBL4115680 | 0.80 | DGAT2 (0.47) | — | |
| SCHEMBL1754318 | 0.78 | KMT2A (0.40) | KMT2AMEN1NPC1RAB9ANTRK1 | |
| SCHEMBL1754393 | 0.77 | CNR2 (0.41) | KMT2AMEN1NPC1RAB9ANTRK1 | |
| SCHEMBL1753988 | 0.76 | CNR1 (0.48) | KMT2AMEN1NPC1RAB9ANTRK1 | |
| SCHEMBL2084475 | 0.76 | CNR1 (0.48) | KMT2AMEN1NPC1RAB9ANTRK1 | |
| SCHEMBL4709558 | 0.76 | HCRTR1 (0.39) | NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945220-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUNDS AS CANNABINOID RECEPTOR ANTAGONISTS | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007046548-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUNDS AS CANNABINOID RECEPTOR ANTAGONISTS | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-04-26 | — | — | WO | disclosed |