Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL130209 | 0.87 | TSHR (0.37) | THRBCES2TSHRLPAR3LPAR1 | |
| SCHEMBL6652231 | 0.84 | TSHR (0.42) | THRBCES2TSHRLPAR3LPAR1 | |
| SCHEMBL29286569 | 0.84 | TSHR (0.35) | THRBCES2TSHRLPAR3LPAR1 | |
| Methoxymethane SCHEMBL28688110 | 0.82 | TSHR (0.33) | THRBCES2TSHRLPAR3LPAR1 | |
| SCHEMBL8663555 | 0.82 | TSHR (0.40) | THRBCES2TSHRLPAR3LPAR1 | |
| SCHEMBL9233911 | 0.82 | TSHR (0.37) | THRBCES2TSHRLPAR3LPAR1 | |
| SCHEMBL7189663 | 0.79 | TSHR (0.47) | THRBCES2TSHRLPAR3LPAR1 | |
| SCHEMBL8470352 | 0.79 | TSHR (0.47) | THRBCES2TSHRLPAR3LPAR1 | |
| SCHEMBL30381193 | 0.79 | TSHR (0.47) | THRBCES2TSHRLPAR3LPAR1 | |
| SCHEMBL28571235 | 0.79 | TSHR (0.47) | THRBCES2TSHRLPAR3LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1426361-B2 | Novel composition containing a bi-cyclic compound and a glyceride | SUCAMPO AG (CH) | 2015-02-25 | — | — | EP | disclosed |
| EP-1426361-B1 | Novel composition containing a bi-cyclic compound and a glyceride | SUCAMPO AG (CH) | 2008-07-30 | — | — | EP | disclosed |