Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL644646 | 0.86 | TSHR (0.45) | TDP1HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL473225 | 0.85 | TDP1 (0.47) | TDP1HDAC6HDAC1HDAC2HDAC3 | |
| Allylamine SCHEMBL15668051 | 0.84 | HDAC3 (0.34) | TDP1HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL934152 | 0.83 | TDP1 (0.50) | TDP1HDAC6HDAC1HDAC2HDAC3 | |
| Hydrochloric Acid SCHEMBL28201423 | 0.83 | TDP1 (0.46) | TDP1HDAC6HDAC1HDAC2HDAC3 | |
| SCHEMBL25168218 | 0.81 | TDP1 (0.53) | TDP1HDAC6HDAC1HDAC2HDAC8 | |
| SCHEMBL8033386 | 0.81 | TDP1 (0.53) | TDP1HDAC6HDAC1HDAC2HDAC8 | |
| SCHEMBL8507410 | 0.81 | TDP1 (0.53) | TDP1HDAC6HDAC1HDAC2HDAC8 | |
| SCHEMBL22029385 | 0.81 | TDP1 (0.53) | TDP1HDAC6HDAC1HDAC2HDAC8 | |
| SCHEMBL3988979 | 0.81 | TDP1 (0.53) | TDP1HDAC6HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 484 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110498915-B | Simple and controllable synthesis method of alpha-carboxyl-omega-hydroxyl polyether | 华南理工大学 | 2021-09-21 | — | — | CN | claimed |
| WO-2020002136-A1 | CATALYST BASED ON A BETA-SUBSTITUTED ESTER AND USE THEREOF IN A HYDROTREATMENT AND/OR HYDROCRACKING PROCESS | IFP Energies Nouvelles (FR) | 2020-01-02 | — | — | WO | claimed |
| EP-2403920-A2 | A METHOD FOR THE MANUFACTURE OF NANOPARTICLE COMPLEXES AND TRIBLOCK POLYMER LIGANDS AND PRODUCTS THEREOF | Centrum für Angewandte Nanotechnologie (CAN) GmbH (DE) | 2012-01-11 | — | — | EP | claimed |
| WO-2010100118-A2 | A METHOD FOR THE MANUFACTURE OF NANOPARTICLE COMPLEXES AND TRIBLOCK POLYMER LIGANDS AND PRODUCTS THEREOF | CENTRUM FÜR ANGEWANDTE NANOTECHNOLOGIE (CAN) GMBH (DE) | 2010-09-10 | — | — | WO | claimed |
| US-7521396-B2 | Substituted (thioxo)carbonylaminophenyluracils | BAYER CROPSCIENCE AG (DE) | 2009-04-21 | — | — | US | claimed |
| CN-101384601-A | Novel 6-amino-morphinan derivatives, method of manufacturing them and their application as analgesics | ALCASYNN PHARMACEUTICALS GMBH (AT) | 2009-03-11 | — | — | CN | claimed |
| US-20060089262-A1 | Substituted (thioxo)carbonylamino phenyl uraciles | BAYER CROPSCIENCE AG (DE) | 2006-04-27 | — | — | US | claimed |
| US-6956037-B2 | Benzamide derivatives for the treatment of diseases mediated by cytokines | ASTRAZENECA AB (SE) | 2005-10-18 | — | — | US | claimed |
| EP-1503994-A1 | SUBSTITUTED (THIOXO)CARBONYLAMINO PHENYL URACILES | Bayer CropScience AG (DE) | 2005-02-09 | — | — | EP | claimed |
| EP-1077931-B1 | BENZAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES MEDIATED BY CYTOKINES | ASTRAZENECA AB (SE) | 2004-11-17 | — | — | EP | claimed |
| US-20030212068-A1 | Benzamide derivatives for the treatment of diseases mediated by cytokines | ASTRAZENECA AB | 2003-11-13 | — | — | US | claimed |
| WO-2003093244-A1 | SUBSTITUTED (THIOXO)CARBONYLAMINO PHENYL URACILES | BAYER CROPSCIENCE AG (DE) | 2003-11-13 | — | — | WO | claimed |
| US-6579872-B1 | Such as TNF, in particular of TNF alpha, and various interleukins, in particular IL-1; N-(5-(4-(3-hydroxypropoxy)benzamido)-2-methylphenyl)-3,4-dimethoxybenzamide | ASTRAZENECA AB (SE) | 2003-06-17 | — | — | US | claimed |
| EP-1077931-A1 | BENZAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES MEDIATED BY CYTOKINES | AstraZeneca AB (SE) | 2001-02-28 | — | — | EP | claimed |
| WO-1999059959-A1 | BENZAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES MEDIATED BY CYTOKINES | ASTRAZENECA AB (SE) | 1999-11-25 | — | — | WO | claimed |
| CN-122070276-A | Prodrugs of xanomeline, prodrugs of trospium chloride and methods of using the same | 人类生物科学股份有限公司 | 2026-05-19 | — | — | CN | disclosed |
| EP-3972649-B1 | MCL-1 INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE | NOVARTIS AG (CH) | 2026-05-13 | — | — | EP | disclosed |
| WO-1987001707-A1 | ANTIHYPERTENSIVE AGENTS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THE PREPARATION OF THE AGENTS AND COMPOSITIONS | SCHERING CORPORATION (US) | 1987-03-26 | — | — | WO | disclosed |
| US-4472300-A | ANTIMICROBIAL | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| US-4207234-A | 4-Unsubstituted azetidinone derivatives and process for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212068-A1 | Benzamide derivatives for the treatment of diseases mediated by cytokines | IL2, IL6, IL6ST | TDP1 3681/4885HDAC6 98/4885HDAC1 133/4885 |
| US-20060089262-A1 | Substituted (thioxo)carbonylamino phenyl uraciles | NQO2, TYMP, DPYD | TDP1 36/4885HDAC6 2829/4885HDAC1 3286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.