SCHEMBL644646

SCHEMBL644646

CC(C)(C)OC(=O)CCC(=O)OC(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.45
STING1 Q86WV6 1/20 0.42
HDAC6 Q9UBN7 3/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC2 Q92769 2/20 0.41
HDAC3 O15379 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
DGAT1 O75907 1/20 0.40
CYP2D6 P10635 1/20 0.38
EPHX2 P34913 1/20 0.38
CA2 P00918 2/20 0.36
CA12 O43570 1/20 0.36
CA14 Q9ULX7 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 1/20 0.35
ADRA2A P08913 1/20 0.35
ADRA1A P35348 1/20 0.35
GAA P10253 1/20 0.35
CA1 P00915 1/20 0.34
CA7 P43166 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25226400 0.92 TSHR (0.39) TSHRSTING1HDAC6HDAC1HDAC2
SCHEMBL3630266 0.89 ALDH1A1 (0.50) TSHRSTING1HDAC6HDAC1HDAC2
SCHEMBL2904495 0.89 TSHR (0.65) TSHRSTING1DGAT1CYP2D6CA2
SCHEMBL631111 0.89 EGLN1 (0.48) TSHRSTING1HDAC6HDAC1HDAC2
SCHEMBL15634991 0.89 ADRA2A (0.39) TSHRSTING1HDAC6HDAC1HDAC2
SCHEMBL6447333 0.89 STING1 (0.38) TSHRSTING1HDAC6HDAC1HDAC2
SCHEMBL1639757 0.88 TSHR (0.50) TSHRSTING1HDAC6HDAC1HDAC2
SCHEMBL134923 0.88 EPHX2 (0.46) TSHRSTING1HDAC6HDAC1HDAC2
SCHEMBL1926081 0.87 STING1 (0.37) TSHRSTING1HDAC6HDAC1HDAC2
Chloromethane SCHEMBL3415691 0.87 EGLN1 (0.46) TSHRSTING1HDAC6HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11873407-B2 Diketopyrrolopyrrole pigment compound having high weathering resistance and preparation method therof CINIC CHEMICALS (SHANGHAI) CO., LTD. (CN) 2024-01-16 US claimed
CN-116199995-A High-fluidity polypropylene resin composition and molded article made from the same 韩华道达尔能源有限公司 2023-06-02 CN claimed
CN-113121496-A Method for preparing bioactive (S) - (-) -nicotine 刘双红 2021-07-16 CN claimed
US-20210179855-A1 DIKETOPYRROLOPYRROLE PIGMENT COMPOUND HAVING HIGH WEATHERING RESISTANCE, PREPARATION METHOD THERFOR, AND USE THEROF CINIC CHEMICALS (SHANGHAI) CO., LTD. (CN) 2021-06-17 US claimed
EP-3733783-A1 DIKETOPYRROLOPYRROLE PIGMENT COMPOUND HAVING HIGH WEATHER RESISTANCE, PREPARATION METHOD THEREFOR AND USE THEREOF Cinic Chemicals Shanghai Co. Ltd. (CN) 2020-11-04 EP claimed
CN-102822152-A Novel 1,3-oxazolidine compounds and their use as renin inhibitors NOVADEX PHARMACEUTICALS AB 2012-12-12 CN claimed
US-5914426-A Process for the preparation of di-tert-butyl succinate CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-06-22 US claimed
CN-1196350-A Process for preparation of di-tert-butyl succinate CIBA GEIGY AG (CH) 1998-10-21 CN claimed
JP-10324663-A None JP disclosed
US-20260146129-A1 BIO-BASED SUCCINIC ACID COMPOSITION, PREPARATION METHOD THEREFOR, AND POLYESTER PREPARED THEREFROM SHANGHAI KINGFA SCIENCE & TECHNOLOGY CO., LTD. (CN) 2026-05-28 US disclosed
US-20260146267-A1 BIO-BASED SUCCINIC ACID COMPOSITION, PREPARATION METHOD THEREFOR, AND USE THEREOF Zhuhai Kingfa Biomaterial Co., Ltd. (CN) 2026-05-28 US disclosed
US-20260146126-A1 SUCCINIC ACID COMPOSITION, POLYESTER PREPARED THEREFROM, AND POLYESTER COMPOSITE MATERIAL Zhuhai Kingfa Biomaterial Co., Ltd. (CN) 2026-05-28 US disclosed
EP-4748822-A2 BIO-BASED SUCCINIC ACID COMPOSITION, PREPARATION METHOD THEREFOR, AND USE THEREOF Zhuhai Kingfa Biomaterial Co., Ltd. (CN) 2026-05-27 EP disclosed
EP-4748823-A1 BIO-BASED SUCCINIC ACID COMPOSITION, PREPARATION METHOD THEREFOR, AND POLYESTER PREPARED THEREFROM Shanghai Kingfa Science & Technology Co., Ltd (CN) 2026-05-27 EP disclosed
EP-0163442-A1 Process for the preparation of esters of dicarboxylic acids The British Petroleum Company p.l.c. (GB) 1985-12-04 EP disclosed
US-4414153-A 1,3-Dithietane-2-carboxylic acid penicillin and cephalosporin derivatives YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1983-11-08 US disclosed
US-4404373-A Process for the preparation of 7α-methoxy-7β-(1,3-diethietane-2-carboxamido)cephalosporanic acid derivatives YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1983-09-13 US disclosed
US-4263432-A ANTIBIOTICS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1981-04-21 US disclosed
US-4198339-A INTERMEDIATES FOR PENICILLINS AND CEPHALOSPORINS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1980-04-15 US disclosed
US-4085274-A OXIDIZING CYCLODODECEN-1-YLPROPIONIC ACID DERIVATIVE DAICEL LTD. (JA) 1978-04-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146267-A1 BIO-BASED SUCCINIC ACID COMPOSITION, PREPARATION METHOD THEREFOR, AND USE THEREOF SUCLA2, SUCLG2, LDHA TSHR 4522/4885STING1 3756/4885HDAC6 4052/4885
US-20260146126-A1 SUCCINIC ACID COMPOSITION, POLYESTER PREPARED THEREFROM, AND POLYESTER COMPOSITE MATERIAL MTOR, RICTOR, SQSTM1 TSHR 4879/4885STING1 2705/4885HDAC6 3293/4885
US-20260146129-A1 BIO-BASED SUCCINIC ACID COMPOSITION, PREPARATION METHOD THEREFOR, AND POLYESTER PREPARED THEREFROM SUCLA2, SUCNR1, SUCLG2 TSHR 4802/4885STING1 4160/4885HDAC6 4026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.