Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 6/20 | 0.44 |
| ▸ | HTR2C | P28335 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | CD44 | P16070 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14136774 | 0.85 | ADRA1D (0.38) | HTR2BHTR2CPNMTADORA2AADORA1 | |
| SCHEMBL14136742 | 0.79 | SYK (0.37) | HTR2BHTR2CKCNH2PNMTCD44 | |
| SCHEMBL23460842 | 0.76 | PNMT (0.40) | KCNH2PNMTCD44MAOB | |
| SCHEMBL22502985 | 0.76 | PNMT (0.43) | PNMTCD44MAOB | |
| SCHEMBL29321156 | 0.70 | PARP11 (0.54) | HTR2BHTR2CPNMTCD44MAOB | |
| SCHEMBL3252513 | 0.70 | PARP11 (0.54) | HTR2BHTR2CPNMTCD44MAOB | |
| SCHEMBL28836952 | 0.70 | PNMT (0.41) | HTR2CPNMTCD44MAOB | |
| SCHEMBL9437061 | 0.69 | HTR2C (0.46) | HTR2BHTR2CPNMTCD44MAOB | |
| SCHEMBL12339922 | 0.69 | HRH3 (0.40) | PNMTALDH1A1ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL27149019 | 0.69 | PNMT (0.37) | PNMTCHRM3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1589970-A4 | PHARMACEUTICAL COMPOSITIONS COMPRISING THIENO ¬2,3-C PYRIDINE DERITIVES AND USE THEREOF | RIMONYX PHARMACEUTICALS LTD (IL) | 2008-05-21 | — | — | EP | claimed |
| JP-2006516610-A | — | — | 2006-07-06 | — | — | JP | claimed |
| EP-1589970-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING THIENO [2,3-C]PYRIDINE DERITIVES AND USE THEREOF | Rimonyx Pharmaceuticals Ltd. (IL) | 2005-11-02 | — | — | EP | claimed |
| WO-2004069149-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING THIENO[2,3-C]PYRIDINE DERIVATIVES AND USE THEREOF | RIMONYX PHARMACEUTICALS LTD. (IL) | 2004-08-19 | — | — | WO | claimed |