Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4709695 | 0.94 | CYP3A4 (0.33) | CYP3A4DGAT2LMNATP53MAPT | |
| SCHEMBL4095980 | 0.84 | PTGDR (0.33) | CYP3A4DGAT2LMNATP53MAPT | |
| SCHEMBL4709531 | 0.64 | CYP3A4 (0.35) | CYP3A4LMNATP53MAPTMEN1 | |
| SCHEMBL4271062 | 0.59 | ACP1 (0.39) | LMNATP53MAPTMEN1KMT2A | |
| SCHEMBL3069012 | 0.56 | FFAR1 (0.47) | MAPTMEN1KMT2AFFAR1KCNA5 | |
| SCHEMBL11183822 | 0.54 | CHRNB2 (0.44) | CYP3A4LMNAMAPTMEN1KMT2A | |
| SCHEMBL1581284 | 0.54 | ACP1 (0.53) | CYP3A4LMNATP53MAPTMEN1 | |
| SCHEMBL11612621 | 0.53 | ATM (0.77) | CYP3A4KMT2ACTSLCTSSKCNA5 | |
| SCHEMBL7057097 | 0.53 | GAA (0.47) | CYP3A4TP53THRBMEN1KMT2A | |
| SCHEMBL6491361 | 0.53 | ITGB3 (0.60) | KMT2AFFAR1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1903045-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-03-26 | — | — | EP | disclosed |