Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2824003 | 0.84 | IDH1 (0.37) | ALDH1A1IDH1MAPK1 | |
| SCHEMBL1337511 | 0.81 | IDH1 (0.37) | ALDH1A1IDH1MAPK1 | |
| SCHEMBL4711671 | 0.78 | ALDH1A1 (0.45) | ALDH1A1RECQLIDH1MAPK1CACNA1G | |
| SCHEMBL15878015 | 0.75 | IDH1 (0.49) | ALDH1A1IDH1MAPK1 | |
| SCHEMBL5325661 | 0.71 | IDH1 (0.32) | ALDH1A1IDH1MAPK1 | |
| SCHEMBL2826099 | 0.69 | ALDH1A1 (0.48) | ALDH1A1IDH1MAPK1 | |
| SCHEMBL4048718 | 0.67 | KDM4E (0.62) | ALDH1A1MAPK1 | |
| SCHEMBL1338558 | 0.66 | ALDH1A1 (0.51) | ALDH1A1IDH1MAPK1 | |
| SCHEMBL19734867 | 0.66 | RECQL (0.38) | ALDH1A1RECQL | |
| SCHEMBL13172069 | 0.66 | KDM4E (0.42) | ALDH1A1IDH1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221096-A1 | Pyrido[3' ,2':4,5]Furo[3,2-d]Pyrimidine Derivatives | LABORATORIOS ALMIRALL, S.A. (ES) | 2008-09-11 | — | — | US | disclosed |
| EP-1913003-A1 | NEW PYRIDO[3',2':4,5]FURO[3,2-d]PYRIMIDINE DERIVATIVES | Laboratorios Almirall, S.A. (ES) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007017078-A1 | NEW PYRIDO[3',2':4,5]FURO[3,2-d]PYRIMIDINE DERIVATIVES | LABORATORIOS ALMIRALL, S.A. (ES) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221096-A1 | Pyrido[3' ,2':4,5]Furo[3,2-d]Pyrimidine Derivatives | NR1H2, CBR3, NR4A1 | ALDH1A1 2625/4885RECQL 492/4885IDH1 547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.