Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SQOR | Q9Y6N5 | 8/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19734865 | 0.82 | MEN1 (0.40) | ALDH1A1KDM4EMEN1GALR3CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL19717539 | 0.81 | MEN1 (0.39) | ALDH1A1KDM4EMEN1GALR3CYP1A2 | |
| Hydrochloric Acid SCHEMBL7021906 | 0.71 | IKBKB (0.40) | ALDH1A1KDM4EMEN1GALR3CYP1A2 | |
| SCHEMBL7022233 | 0.69 | SQOR (0.57) | SQORALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL19734514 | 0.67 | KDM4E (0.44) | ALDH1A1KDM4EMEN1GALR3CYP1A2 | |
| SCHEMBL4709710 | 0.66 | ALDH1A1 (0.36) | RECQLALDH1A1 | |
| SCHEMBL7017342 | 0.65 | ALDH1A1 (0.52) | SQORALDH1A1HSD17B10ADORA2AADORA1 | |
| SCHEMBL15174110 | 0.65 | RECQL (0.53) | RECQLSQORMAPK8MAPK9ALDH1A1 | |
| SCHEMBL4068894 | 0.64 | RECQL (0.55) | RECQLSQORMAPK8MAPK9ALDH1A1 | |
| SCHEMBL14251855 | 0.62 | ALDH1A1 (0.41) | RECQLALDH1A1KDM4EMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017216726-A1 | SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-12-21 | — | — | WO | disclosed |
| WO-2017216727-A1 | SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-12-21 | — | — | WO | disclosed |