Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 5/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.43 |
| ▸ | PRKACA | P17612 | 4/20 | 0.43 |
| ▸ | CDK2 | P24941 | 4/20 | 0.43 |
| ▸ | GSK3B | P49841 | 4/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.43 |
| ▸ | FLT3 | P36888 | 3/20 | 0.43 |
| ▸ | CLK2 | P49760 | 3/20 | 0.43 |
| ▸ | PRKX | P51817 | 3/20 | 0.43 |
| ▸ | JAK3 | P52333 | 3/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.43 |
| ▸ | MAP4K2 | Q12851 | 3/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.43 |
| ▸ | STK17A | Q9UEE5 | 3/20 | 0.43 |
| ▸ | MAP4K5 | Q9Y4K4 | 3/20 | 0.43 |
| ▸ | PIM1 | P11309 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4707457 | 0.92 | CDC7 (0.42) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL4707214 | 0.91 | CDC7 (0.39) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL4709645 | 0.87 | CDC7 (0.38) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL4706990 | 0.86 | CDC7 (0.44) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL4706961 | 0.86 | IDO1 (0.40) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL4707454 | 0.85 | CDC7 (0.38) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL4705173 | 0.85 | NR1H2 (0.39) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL4705490 | 0.84 | P2RX7 (0.36) | CDC7GSK3BCLK2CDK8NR1H2 | |
| SCHEMBL4707007 | 0.84 | CDC7 (0.37) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL4705832 | 0.82 | GRM2 (0.38) | CDC7MAP4K4PRKACACDK2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501809-B1 | TRIAZOLE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-01-16 | — | — | EP | disclosed |