Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.34 |
| ▸ | MELK | Q14680 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15374852 | 0.92 | ALDH1A1 (0.38) | P2RX7TP53GRM1POLBMAPT | |
| SCHEMBL12060112 | 0.85 | ALDH1A1 (0.38) | P2RX7POLBMAPTALDH1A1KDM4E | |
| SCHEMBL470985 | 0.82 | ALDH1A1 (0.39) | P2RX7GRM1POLBGAAMAPT | |
| SCHEMBL15374840 | 0.76 | GAA (0.40) | GRM1POLBGAAALDH1A1KDM4E | |
| SCHEMBL15374842 | 0.69 | PGK1 (0.42) | GAAKDM4E | |
| SCHEMBL10053817 | 0.69 | GAA (0.39) | POLBGAAALDH1A1KDM4ELMNA | |
| SCHEMBL471042 | 0.69 | KDM4E (0.43) | GRM1GAAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL12060039 | 0.67 | IDH1 (0.34) | POLBGAAALDH1A1KDM4EOPRK1 | |
| SCHEMBL12043375 | 0.65 | ALDH1A1 (0.41) | P2RX7TP53POLBGAAMAPT | |
| SCHEMBL10053819 | 0.65 | GAA (0.42) | P2RX7TP53POLBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012033101-A1 | QUINOXALINE COMPOUND | アステラス製薬株式会社 (JP) | 2012-03-15 | — | — | WO | disclosed |