SCHEMBL471095

SCHEMBL471095

CCOc1ccc([N+](=O)[O-])c(NC)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.63
ALDH1A1 P00352 3/20 0.63
LMNA P02545 2/20 0.63
RAB9A P51151 8/20 0.50
NPC1 O15118 7/20 0.50
SMN1; SMN2 Q16637 7/20 0.50
MAPK1 P28482 4/20 0.50
PKM P14618 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
POLB P06746 1/20 0.50
KMT2A Q03164 5/20 0.49
MEN1 O00255 3/20 0.49
NFKB1 P19838 1/20 0.48
NFKB2 Q00653 1/20 0.48
RELA Q04206 1/20 0.48
RECQL P46063 1/20 0.48
CYP1A2 P05177 2/20 0.47
GAA P10253 1/20 0.47
TP53 P04637 1/20 0.47
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4011443 0.88 MAPT (0.65) MAPTALDH1A1LMNARAB9ANPC1
SCHEMBL7402604 0.86 MAPT (0.66) MAPTALDH1A1LMNARAB9ANPC1
SCHEMBL470841 0.86 MAPT (0.47) MAPTALDH1A1LMNASMN1; SMN2PKM
SCHEMBL111211 0.84 MAPT (0.49) MAPTALDH1A1LMNARAB9ANPC1
SCHEMBL29392600 0.84 MAPT (0.49) MAPTALDH1A1LMNARAB9ANPC1
SCHEMBL13211382 0.83 MAPT (0.53) MAPTALDH1A1LMNASMN1; SMN2MAPK1
SCHEMBL11143202 0.83 SMN1; SMN2 (0.47) MAPTALDH1A1LMNARAB9ANPC1
SCHEMBL2654219 0.82 ALDH1A1 (0.45) MAPTALDH1A1LMNASMN1; SMN2L3MBTL1
SCHEMBL2776809 0.82 MAPT (0.57) MAPTALDH1A1LMNARAB9ANPC1
SCHEMBL15064772 0.82 MAPT (0.48) MAPTALDH1A1LMNARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107548301-A Contain composition of the menthol as soothing agent 西姆莱斯股份公司 2018-01-05 CN disclosed
CN-105407869-A Cosmetic treatment method using a coating based on a copolymer containing polyamide blocks and polyether blocks OREAL 2016-03-16 CN disclosed
EP-2791252-A1 TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE L'OREAL (FR) 2014-10-22 EP disclosed
CN-101744747-B Process and device for lightening or direct or oxidative dyeing with an aqueous composition rich in fatty compounds OREAL 2013-07-24 CN disclosed
WO-2013087768-A1 TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE L'OREAL (FR) 2013-06-20 WO disclosed
WO-2012033091-A1 PROCESS FOR PREPARING BENZOIC ACID ESTERS 第一三共株式会社 (JP) 2012-03-15 WO disclosed
CN-101909587-A Composition for the oxidation dyeing of human keratin fibres comprising a fatty alcohol, a fatty ester and a cationic surfactant, method and device for using same OREAL 2010-12-08 CN disclosed
CN-101744747-A Process and kit for lightening or direct or oxidative dyeing keratinic fibers with an aqueous composition rich in fatty compounds OREAL 2010-06-23 CN disclosed
CN-101744748-A Process for lightening or process for direct dyeing or oxidation dyeing of keratin fibers in the presence of ammonium salt and device therefor OREAL 2010-06-23 CN disclosed
CN-101744746-A Process for lightening or lightening direct dyeing or oxidation dyeing in the presence of at least one organic amine and at least one inorganic base, and device therefor OREAL 2010-06-23 CN disclosed
EP-2076237-A1 COMPOSITION FOR OXIDATION DYEING KERATINOUS FIBRES COMPRISING AT LEAST ONE PARTICULAR AMMONIUM SALT DERIVED FROM 18MEA, AND A COLOURING METHOD USING THE COMPOSITION L'Oreal (FR) 2009-07-08 EP disclosed
WO-2008049767-A1 COMPOSITION FOR OXIDATION DYEING KERATINOUS FIBRES COMPRISING AT LEAST ONE PARTICULAR AMMONIUM SALT DERIVED FROM 18MEA, AND A COLOURING METHOD USING THE COMPOSITION L'OREAL (FR) 2008-05-02 WO disclosed