Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL471095 | 0.86 | MAPT (0.63) | MAPTKMT2AALDH1A1LMNACYP1A2 | |
| SCHEMBL4011443 | 0.84 | MAPT (0.65) | MAPTKMT2AALDH1A1LMNACYP1A2 | |
| SCHEMBL29392600 | 0.82 | MAPT (0.49) | MAPTKMT2AALDH1A1LMNACYP1A2 | |
| SCHEMBL111211 | 0.82 | MAPT (0.49) | MAPTKMT2AALDH1A1LMNACYP1A2 | |
| SCHEMBL13211382 | 0.82 | MAPT (0.53) | MAPTKMT2AALDH1A1LMNACYP1A2 | |
| SCHEMBL3249779 | 0.81 | SMN1; SMN2 (0.49) | MAPTKMT2AALDH1A1LMNAPOLB | |
| SCHEMBL2654219 | 0.81 | ALDH1A1 (0.45) | MAPTKMT2AALDH1A1LMNACYP1A2 | |
| SCHEMBL15064772 | 0.81 | MAPT (0.48) | MAPTKMT2AALDH1A1LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL9760985 | 0.81 | MAPT (0.48) | MAPTKMT2AALDH1A1LMNACYP1A2 | |
| SCHEMBL487216 | 0.81 | AKR1C3 (0.57) | MAPTKMT2AALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130204009-A1 | PROCESS FOR PREPARING BENZOIC ACID ESTERS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-08-08 | — | — | US | disclosed |
| US-20130204009-A1 | PROCESS FOR PREPARING BENZOIC ACID ESTERS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-08-08 | — | — | US | disclosed |
| EP-2615081-A1 | PROCESS FOR PREPARING BENZOIC ACID ESTERS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012033091-A1 | PROCESS FOR PREPARING BENZOIC ACID ESTERS | 第一三共株式会社 (JP) | 2012-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130204009-A1 | PROCESS FOR PREPARING BENZOIC ACID ESTERS | HPD, CYP2B6, PAH | MAPT 2785/4885KMT2A 825/4885ALDH1A1 379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.