Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 13/20 | 0.64 |
| ▸ | CA2 | P00918 | 6/20 | 0.58 |
| ▸ | CA1 | P00915 | 5/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA5A | P35218 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.58 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23014659 | 0.82 | PTGES2 (0.61) | PTGES2CA2CA1 | |
| SCHEMBL12768022 | 0.82 | PSIP1 (0.73) | PSIP1 | |
| SCHEMBL1127421 | 0.81 | CA2 (0.62) | PTGES2CA2CA1CA9CA12 | |
| SCHEMBL10910563 | 0.80 | PTGES2 (0.57) | PTGES2CA2CA1CA9CA12 | |
| SCHEMBL3763309 | 0.79 | CA2 (0.60) | PTGES2CA2CA1CA9CA12 | |
| SCHEMBL3776686 | 0.78 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3783849 | 0.78 | PTGES2 (1.00) | PTGES2CA2CA1CA9CA12 | |
| SCHEMBL1290833 | 0.77 | PSIP1 (0.61) | PTGES2PSIP1 | |
| SCHEMBL11722241 | 0.77 | PSIP1 (0.61) | PTGES2CA1CA9CA12PSIP1 | |
| SCHEMBL7354878 | 0.76 | CA2 (0.59) | PTGES2CA2CA1CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879877-A2 | ANTIMICROBIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | claimed |
| WO-2006117762-A2 | ANTIMICROBIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | claimed |