Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.49 |
| ▸ | RELA | Q04206 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531612 | 0.88 | MAOB (0.57) | MAOBNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL2207993 | 0.83 | LIPG (0.52) | MAOBNPC1RAB9AFAAHSMN1; SMN2 | |
| SCHEMBL2209377 | 0.83 | LIPG (0.52) | MAOBNPC1RAB9AFAAHSMN1; SMN2 | |
| SCHEMBL2207176 | 0.81 | MAOB (0.51) | MAOBNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL2203630 | 0.81 | MAOB (0.51) | MAOBNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL8672260 | 0.80 | MAOB (0.52) | MAOBNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL7956150 | 0.79 | MEN1 (0.55) | MAOBNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL7828765 | 0.78 | RAB9A (0.53) | MAOBNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL6084707 | 0.75 | MAOB (0.76) | MAOBNPC1RAB9AFAAHSMN1; SMN2 | |
| SCHEMBL21490032 | 0.75 | MAOB (0.76) | MAOBNPC1RAB9AFAAHSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101180298-A | Novel antibiotic derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2008-05-14 | — | — | CN | disclosed |
| EP-1888574-A2 | NEW ANTIBIOTIC DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006126171-A2 | NEW ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2006-11-30 | — | — | WO | disclosed |