Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.33 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3894535 | 0.82 | HDAC6 (0.36) | MAPTHPGDTSHRHDAC6HDAC3 | |
| SCHEMBL5285565 | 0.82 | HDAC6 (0.36) | MAPTHPGDTSHRHDAC6HDAC3 | |
| SCHEMBL3897246 | 0.79 | HTR2C (0.35) | HTR2CHTR2BALDH1A1MAPTHPGD | |
| SCHEMBL3897247 | 0.79 | HTR2C (0.35) | HTR2CHTR2BALDH1A1MAPTHPGD | |
| SCHEMBL13866956 | 0.78 | EPHX2 (0.33) | ALDH1A1 | |
| SCHEMBL4709012 | 0.77 | MEN1 (0.34) | HTR2CHTR2BALDH1A1MAPTHPGD | |
| SCHEMBL4097112 | 0.68 | MEN1 (0.43) | MAPTHPGDPDE4BTSHRMEN1 | |
| SCHEMBL4097113 | 0.68 | MEN1 (0.43) | MAPTHPGDPDE4BTSHRMEN1 | |
| SCHEMBL3898095 | 0.68 | HDAC6 (0.43) | HPGDTSHRHDAC6PIK3CDPIK3R2 | |
| SCHEMBL3889272 | 0.65 | HDAC10 (0.35) | HTR2CHTR2BALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863479-B1 | TETRAHYDROTHIOPYRANO PYRAZOLE CANNABINOID MODULATORS CROSS REFERENCE TO RELATED APPLICATIONS | JANSSEN PHARMACEUTICA NV (BE) | 2008-12-10 | — | — | EP | disclosed |