Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13876771 | 0.86 | LMNA (0.36) | MEN1KMT2AALDH1A1LMNAHTR2C | |
| SCHEMBL3888576 | 0.82 | HTR7 (0.33) | MEN1KMT2AALDH1A1LMNAHTR2C | |
| SCHEMBL13866965 | 0.82 | CNR2 (0.38) | MEN1KMT2A | |
| SCHEMBL13866971 | 0.82 | CNR2 (0.38) | MEN1KMT2A | |
| SCHEMBL13866975 | 0.78 | CNR2 (0.33) | ALDH1A1 | |
| SCHEMBL13866978 | 0.78 | CNR2 (0.33) | ALDH1A1 | |
| SCHEMBL3897247 | 0.78 | HTR2C (0.35) | MEN1KMT2AALDH1A1LMNAHTR2C | |
| SCHEMBL3897246 | 0.78 | HTR2C (0.35) | MEN1KMT2AALDH1A1LMNAHTR2C | |
| SCHEMBL4711770 | 0.77 | HTR2C (0.34) | MEN1KMT2AALDH1A1LMNAHTR2C | |
| SCHEMBL3890975 | 0.68 | HPGD (0.41) | MEN1KMT2AALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863479-B1 | TETRAHYDROTHIOPYRANO PYRAZOLE CANNABINOID MODULATORS CROSS REFERENCE TO RELATED APPLICATIONS | JANSSEN PHARMACEUTICA NV (BE) | 2008-12-10 | — | — | EP | disclosed |