Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8651114 | 0.70 | TDP1 (0.50) | MAPTTDP1ABL1RIN1KDM4E | |
| SCHEMBL5500844 | 0.67 | MAPT (0.48) | MAPTTDP1ABL1RIN1KDM4E | |
| SCHEMBL11145933 | 0.65 | TDP1 (0.72) | MAPTTDP1ABL1RIN1KDM4E | |
| SCHEMBL924239 | 0.62 | TDP1 (0.58) | MAPTTDP1ABL1RIN1KDM4E | |
| SCHEMBL192058 | 0.62 | TDP1 (0.68) | MAPTTDP1ABL1RIN1KDM4E | |
| SCHEMBL18106267 | 0.62 | TDP1 (0.58) | MAPTTDP1ABL1RIN1KDM4E | |
| SCHEMBL36249 | 0.61 | MAPT (0.39) | MAPTTDP1ABL1RIN1 | |
| SCHEMBL36250 | 0.61 | MAPT (0.39) | MAPTTDP1ABL1RIN1 | |
| SCHEMBL16859574 | 0.60 | OPRM1 (0.44) | MAPTTDP1ABL1RIN1KDM4E | |
| SCHEMBL18106282 | 0.60 | TDP1 (0.64) | MAPTTDP1ABL1RIN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1725558-A4 | METHOD FOR PREPARING COMPOUNDS COMPRISING CUCURBITURIL GROUPS | NEWSOUTH INNOVATIONS PTY LTD (AU) | 2008-07-30 | — | — | EP | disclosed |
| US-20070287836-A1 | Method for Preparing Compounds Comprising Cucurbituril Groups | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2007-12-13 | — | — | US | disclosed |
| EP-1725558-A1 | METHOD FOR PREPARING COMPOUNDS COMPRISING CUCURBITURIL GROUPS | Newsouth Innovations Pty Limited (AU) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005090351-A1 | METHOD FOR PREPARING COMPOUNDS COMPRISING CUCURBITURIL GROUPS | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2005-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287836-A1 | Method for Preparing Compounds Comprising Cucurbituril Groups | ACSL6, AGL, LIPA | MAPT 3543/4885TDP1 4400/4885ABL1 866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.