SCHEMBL5500844

SCHEMBL5500844

O=C1NC2NC(=O)N(Cl)C2N1

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.48
TDP1 Q9NUW8 4/20 0.44
ABL1 P00519 3/20 0.44
RIN1 Q13671 3/20 0.44
KDM4E B2RXH2 2/20 0.36
KMT2A Q03164 1/20 0.36
GAA P10253 1/20 0.32
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1321551 0.72 ABL1 (0.35) MAPTTDP1ABL1RIN1GAA
SCHEMBL18106287 0.71 TDP1 (0.58) MAPTTDP1ABL1RIN1KDM4E
SCHEMBL11145933 0.70 TDP1 (0.72) MAPTTDP1ABL1RIN1KDM4E
SCHEMBL18106267 0.67 TDP1 (0.58) MAPTTDP1ABL1RIN1KDM4E
SCHEMBL192058 0.67 TDP1 (0.68) MAPTTDP1ABL1RIN1KDM4E
SCHEMBL4712146 0.67 MAPT (0.44) MAPTTDP1ABL1RIN1KDM4E
SCHEMBL924239 0.67 TDP1 (0.58) MAPTTDP1ABL1RIN1KDM4E
SCHEMBL36250 0.66 MAPT (0.39) MAPTTDP1ABL1RIN1
SCHEMBL16859574 0.64 OPRM1 (0.44) MAPTTDP1ABL1RIN1KDM4E
SCHEMBL18106282 0.64 TDP1 (0.64) MAPTTDP1ABL1RIN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113769121-B Radiotherapeutic medicine for diseases caused by coronavirus or influenza virus and preparation method thereof 中国原子能科学研究院 2022-10-28 CN claimed
CN-113769121-A Radiotherapeutic medicine for diseases caused by coronavirus or influenza virus and preparation method thereof 中国原子能科学研究院 2021-12-10 CN claimed
CN-109453400-B Radioactive iodine labeled gold nano material and preparation method and application thereof 中国药科大学 2021-07-13 CN claimed
WO-2007075449-A2 COATING CONTAINING DENATURED ALOE VERA, FOR COVERING EITHER CHLORINE-GENERATING COMPOSITIONS OR OTHER HAZARDOUS CHEMICALS AND METHOD MAKING DEWALD AARON (US) 2007-07-05 WO claimed
US-20070141341-A1 Coating containing denatured aloe vera, for covering either chlorine-generating compositions or other hazardous chemicals and method for making DEWALD AARON 2007-06-21 US claimed
US-5591692-A DISINFECTION WITH MIXTURE OF CHLORINE- AND GLYCOLURIL-SOURCES BIO-LAB, INC. (US) 1997-01-07 US claimed
CN-117695388-A Tumor extracellular ATP response type nano assembly and preparation method and application thereof 中国药科大学 2024-03-15 CN disclosed
CN-110903392-B Monoclonal antibodies that specifically bind to GITR BIOCAD股份公司 2024-02-13 CN disclosed
CN-117460528-A anti-CLDN 18.2 antibody conjugates 苏州创胜医药集团有限公司 2024-01-26 CN disclosed
CN-115808338-A Method for marking nano quantum dots by radioactive isotope 中国科学院高能物理研究所 2023-03-17 CN disclosed
CN-107118767-B Radionuclide iodine labeled fluorescent carbon dot, synthesis method and application 厦门大学 2023-01-10 CN disclosed
CN-113769121-B Radiotherapeutic medicine for diseases caused by coronavirus or influenza virus and preparation method thereof 中国原子能科学研究院 2022-10-28 CN disclosed
CN-113769121-A Radiotherapeutic medicine for diseases caused by coronavirus or influenza virus and preparation method thereof 中国原子能科学研究院 2021-12-10 CN disclosed
WO-1992013528-A1 DESINFECTANT FOR THE TREATMENT OF WATER SYSTEMS BIO-LAB, INC. (US) 1992-08-20 WO disclosed
US-5057604-A Binding to protein WASHINGTON UNIVERSITY (US) 1991-10-15 US disclosed
EP-0239896-B1 N,N'-DIHALO-2-IMIDAZOLIDINONES PPG INDUSTRIES, INC. (US) 1990-09-05 EP disclosed
US-4767542-A CHLORO-AND BROMO DERIVATIVES PPG INDUSTRIES, INC. (US) 1988-08-30 US disclosed
EP-0239896-A1 N,N'-Dihalo-2-imidazolidinones PPG INDUSTRIES, INC. (US) 1987-10-07 EP disclosed
US-4681948-A BACTERICIDE PPG INDUSTRIES, INC. (US) 1987-07-21 US disclosed
US-4659669-A GENETIC ENGINEERING REGENTS OF THE UNIV. OF CALIFORNIA (US) 1987-04-21 US disclosed