⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL8981505 | 0.94 | — | — | |
| SCHEMBL12925827 | 0.75 | — | — | |
| SCHEMBL1517262 | 0.72 | — | — | |
| SCHEMBL24763847 | 0.69 | DNM1 (0.61) | — | |
| SCHEMBL21688420 | 0.69 | — | — | |
| Ethylenediamine SCHEMBL30901425 | 0.67 | — | — | |
| Ethylenediamine SCHEMBL10884255 | 0.67 | — | — | |
| Ethylenediamine SCHEMBL10943831 | 0.67 | — | — | |
| Ethylenediamine SCHEMBL37647 | 0.63 | — | — | |
| Ethylenediamine SCHEMBL7085968 | 0.63 | NFKB1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238325-A1 | Artificial Nucleic Acid and Method for Delivery of Nucleic Acid Using the Same | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2024-07-18 | — | — | US | disclosed |
| US-11761009-B2 | Artificial nucleic acid molecules for improved protein expression | CureVac SE (DE) | 2023-09-19 | — | — | US | disclosed |
| WO-2022226420-A9 | AN FC GLYCAN REMODELING FOR SITE-SPECIFIC ANTIBODY CONJUGATION AND APPLICATIONS THEREOF | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2022-12-22 | — | — | WO | disclosed |
| US-20210393755-A1 | NUCLEIC ACID COMPRISING OR CODING FOR A HISTONE STEM-LOOP AND A POLY(A) SEQUENCE OR A POLYADENYLATION SIGNAL FOR INCREASING THE EXPRESSION OF AN ENCODED TUMOUR ANTIGEN | CUREVAC AG (DE) | 2021-12-23 | — | — | US | disclosed |
| US-20210116374-A1 | IN SITU SENSING OF WATER POTENTIAL | CORNELL UNIVERSITY | 2021-04-22 | — | — | US | disclosed |
| EP-3348555-B1 | COMPOSITIONS AND METHODS OF USING THE COMPOSITIONS FOR PLAQUE SOFTENING | ALUMEND LLC (US) | 2020-11-25 | — | — | EP | disclosed |
| EP-3011031-B1 | DELIVERY AND USE OF THE CRISPR-CAS SYSTEMS, VECTORS AND COMPOSITIONS FOR HEPATIC TARGETING AND THERAPY | BROAD INST INC (US) | 2020-09-30 | — | — | EP | disclosed |
| WO-2020058959-A1 | MOTION VECTOR DERIVATION FOR SUB-BLOCK IN AFFINE MODE | BEIJING BYTEDANCE NETWORK TECHNOLOGY CO., LTD. (CN) | 2020-03-26 | — | — | WO | disclosed |
| US-10519125-B2 | Flavagline derivatives | PIERRE FABRE MEDICAMENT (FR) | 2019-12-31 | — | — | US | disclosed |
| WO-2019173761-A1 | C-ABL TYROSINE KINASE INHIBITORY COMPOUND EMBODIMENTS AND METHODS OF MAKING AND USING THE SAME | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2019-09-12 | — | — | WO | disclosed |
| US-20110097559-A1 | SUPRAMOLECULAR BLOCK COPOLYMER COMPOSITIONS FOR SUB-MICRON LITHOGRAPHY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2011-04-28 | — | — | US | disclosed |
| WO-2011027081-A2 | NOVEL DERIVATIVES OF 5,6,7,8-TETRAHYDROINDOLIZINE INHIBITING HSP90, COMPOSITIONS CONTAINING SAME, AND USE THEREOF | SANOFI-AVENTIS (FR) | 2011-03-10 | — | — | WO | disclosed |
| US-7872133-B2 | Tricyclic heterocycle compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-01-18 | — | — | US | disclosed |
| WO-2011004132-A1 | NOVEL HSP90-INHIBITING INDOLE DERIVATIVES, COMPOSITIONS CONTAINING SAID DERIVATIVES, AND USE THEREOF | SANOFI-AVENTIS (FR) | 2011-01-13 | — | — | WO | disclosed |
| US-20100261683-A1 | Selective Inhibitors for Cyclin-Dependent Kinases | EMORY UNIVERSITY | 2010-10-14 | — | — | US | disclosed |
| WO-2010106290-A1 | HSP90 INHIBITING INDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SAME AND USE THEREOF | SANOFI-AVENTIS (FR) | 2010-09-23 | — | — | WO | disclosed |
| WO-2009153516-A1 | NOVEL DERIVATIVES OF PYRROLOINDOLE INHIBITORS OF HSP90, COMPOSITIONS CONTAINING SAME, AND USE THEREOF | SANOFI-AVENTIS (FR) | 2009-12-23 | — | — | WO | disclosed |
| WO-2009122034-A2 | NOVEL HSP90 INHIBITORY CARBAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SAME, AND USE THEREOF | SANOFI-AVENTIS (FR) | 2009-10-08 | — | — | WO | disclosed |
| EP-1457488-B1 | Intermediates for use in the preparation of urea compounds having muscarinic receptor antagonist activity | THERAVANCE INC (US) | 2009-08-12 | — | — | EP | disclosed |
| US-7479536-B1 | Chiral, charged peptide nucleic acid oligomers from cyclic monomers | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2009-01-20 | — | — | US | disclosed |