Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 17/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4713778 | 1.00 | HSD11B1 (0.56) | HSD11B1LMNAKMT2AMGLLHTT | |
| SCHEMBL4711260 | 0.84 | HSD11B1 (0.60) | HSD11B1LMNAKMT2AMGLLHTT | |
| SCHEMBL4711259 | 0.84 | HSD11B1 (0.60) | HSD11B1LMNAKMT2AMGLLHTT | |
| SCHEMBL4715310 | 0.78 | HSD11B1 (0.56) | HSD11B1LMNAKMT2AHTT | |
| SCHEMBL9236780 | 0.69 | HSD11B1 (0.73) | HSD11B1LMNAKMT2AMGLLHTT | |
| SCHEMBL6210786 | 0.69 | HSD11B1 (0.73) | HSD11B1LMNAKMT2AMGLLHTT | |
| SCHEMBL6236172 | 0.69 | HSD11B1 (1.00) | HSD11B1LMNAMGLL | |
| SCHEMBL6209947 | 0.68 | HSD11B1 (1.00) | HSD11B1LMNAKMT2AMGLL | |
| SCHEMBL6208828 | 0.68 | HSD11B1 (0.68) | HSD11B1MGLL | |
| SCHEMBL4712675 | 0.68 | HSD11B1 (0.60) | HSD11B1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998459-B1 | PYRIDINE DERIVATIVES | NOVARTIS AG (CH) | 2008-04-23 | — | — | EP | claimed |
| EP-0998459-B1 | PYRIDINE DERIVATIVES | NOVARTIS AG (CH) | 2008-04-23 | — | — | EP | disclosed |