Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 16/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4712675 | 0.84 | HSD11B1 (0.60) | HSD11B1 | |
| SCHEMBL4715138 | 0.83 | HSD11B1 (0.63) | HSD11B1 | |
| SCHEMBL4714732 | 0.82 | GRM5 (0.47) | — | |
| SCHEMBL7266687 | 0.79 | HSD11B1 (0.52) | HSD11B1LMNAKMT2AALDH1A1HTT | |
| SCHEMBL4713778 | 0.78 | HSD11B1 (0.56) | HSD11B1LMNAKMT2AHTT | |
| SCHEMBL4713775 | 0.78 | HSD11B1 (0.56) | HSD11B1LMNAKMT2AHTT | |
| SCHEMBL4712862 | 0.78 | TP53 (0.46) | LMNA | |
| SCHEMBL4713917 | 0.75 | GRM5 (0.41) | — | |
| SCHEMBL4715216 | 0.74 | GRM5 (0.51) | — | |
| SCHEMBL4711260 | 0.71 | HSD11B1 (0.60) | HSD11B1LMNAKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998459-B1 | PYRIDINE DERIVATIVES | NOVARTIS AG (CH) | 2008-04-23 | — | — | EP | disclosed |