Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3218715 | 0.99 | MEN1 (0.41) | MEN1KMT2AHCRTR1HCRTR2CYP1A2 | |
| SCHEMBL4715918 | 0.93 | MEN1 (0.42) | MEN1KMT2AHCRTR1HCRTR2CYP1A2 | |
| Hydrochloric Acid SCHEMBL3211750 | 0.92 | MEN1 (0.41) | MEN1KMT2AHCRTR1HCRTR2CYP1A2 | |
| SCHEMBL4715041 | 0.85 | EGFR (0.39) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL3214937 | 0.84 | EGFR (0.38) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4717086 | 0.82 | SMN1; SMN2 (0.42) | MEN1KMT2ACYP1A2TDP1KDM4E | |
| Hydrochloric Acid SCHEMBL3198075 | 0.81 | SMN1; SMN2 (0.43) | MEN1KMT2ACYP1A2TDP1KDM4E | |
| SCHEMBL4715098 | 0.75 | HPGD (0.42) | MEN1KMT2AALDH1A1AURKA | |
| SCHEMBL4717313 | 0.75 | CYP1A2 (0.51) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4761613 | 0.74 | GRIN2B (0.38) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917245-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | Abbott GmbH & Co. KG (DE) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007022946-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | ABBOTT GMBH & CO. KG (DE) | 2007-03-01 | — | — | WO | disclosed |