Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3209458 | 0.99 | HPGD (0.41) | HPGDRAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL4761749 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL4715041 | 0.78 | EGFR (0.39) | HPGDSMN1; SMN2TP53TSHRPDGFRB | |
| Hydrochloric Acid SCHEMBL3214937 | 0.77 | EGFR (0.38) | HPGDSMN1; SMN2TP53TSHRLCK | |
| SCHEMBL4718142 | 0.76 | MEN1 (0.59) | MEN1KMT2A | |
| SCHEMBL4714175 | 0.76 | SIGMAR1 (0.44) | HPGDALDH1A1MAPT | |
| SCHEMBL4717086 | 0.75 | SMN1; SMN2 (0.42) | HPGDRAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL4714040 | 0.75 | MEN1 (0.41) | AURKAALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3218715 | 0.74 | MEN1 (0.41) | AURKAALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3198075 | 0.74 | SMN1; SMN2 (0.43) | HPGDRAB9ASMN1; SMN2NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917245-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | Abbott GmbH & Co. KG (DE) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007022946-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | ABBOTT GMBH & CO. KG (DE) | 2007-03-01 | — | — | WO | disclosed |