Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | DHPS | P49366 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4717132 | 0.92 | KDM4E (0.41) | HSP90AA1HSP90AB1PIK3CDNQO2KDM4E | |
| SCHEMBL4718160 | 0.88 | ADCY10 (0.46) | HSP90AA1HSP90AB1PIK3CDNQO2PNP | |
| Hydrochloric Acid SCHEMBL3208099 | 0.88 | MCHR1 (0.49) | NQO2MCHR1TLR8KDM4EPNP | |
| SCHEMBL4716953 | 0.84 | MCHR1 (0.39) | NQO2MCHR1TLR8PNPHTT | |
| SCHEMBL4714041 | 0.83 | PDE10A (0.47) | MCHR1TLR8KDM4EDHFR | |
| SCHEMBL3217299 | 0.82 | TLR8 (0.54) | HSP90AA1HSP90AB1NQO2TLR8 | |
| SCHEMBL4719204 | 0.82 | MCHR1 (0.39) | MCHR1HTTDHFR | |
| SCHEMBL3218819 | 0.81 | NQO2 (0.42) | HSP90AA1HSP90AB1NQO2TLR8DHPS | |
| SCHEMBL4718173 | 0.81 | MPO (0.39) | MCHR1TLR8KDM4EPNPHTT | |
| SCHEMBL3206611 | 0.80 | TLR8 (0.60) | NQO2TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917245-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | Abbott GmbH & Co. KG (DE) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007022946-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | ABBOTT GMBH & CO. KG (DE) | 2007-03-01 | — | — | WO | disclosed |