Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | IDH2 | P48735 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4717987 | 1.00 | TSHR (0.47) | TSHRMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL1853562 | 0.89 | KMT2A (0.50) | TSHRMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL4717989 | 0.86 | MEN1 (0.47) | TSHRMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL4714650 | 0.86 | MEN1 (0.47) | TSHRMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL4714622 | 0.84 | TSHR (0.56) | TSHRMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL4711906 | 0.84 | EPHX1 (0.38) | TRPV1LMNAMAPTMIFALDH1A1 | |
| SCHEMBL4016045 | 0.81 | SMN1; SMN2 (0.42) | TSHRMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL1854854 | 0.81 | SMN1; SMN2 (0.42) | TSHRMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL4019801 | 0.80 | MEN1 (0.47) | TSHRMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL4019374 | 0.80 | MEN1 (0.47) | TSHRMEN1KMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986637-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | Laboratoires Serono SA (CH) | 2008-11-05 | — | — | EP | claimed |
| WO-2007093557-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | LABORATOIRES SERONO S.A. (CH) | 2007-08-23 | — | — | WO | claimed |