Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.39 |
| ▸ | IDH2 | P48735 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | UBE2M | P61081 | 4/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 4/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1854854 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1TSHRHTTKMT2A | |
| SCHEMBL4024326 | 0.90 | MAPK1 (0.46) | SMN1; SMN2TSHRSERPINE1PTGESNR3C1 | |
| SCHEMBL1853297 | 0.89 | SMN1; SMN2 (0.45) | SMN1; SMN2MEN1TSHRHTTKMT2A | |
| SCHEMBL1852104 | 0.88 | KMT2A (0.50) | SMN1; SMN2MEN1TSHRHTTKMT2A | |
| SCHEMBL1856431 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1TSHRHTTKMT2A | |
| SCHEMBL4022922 | 0.87 | EPHX1 (0.39) | SMN1; SMN2TSHRHTTTRPV1SERPINE1 | |
| SCHEMBL1853214 | 0.86 | TSHR (0.43) | SMN1; SMN2MEN1TSHRHTTKMT2A | |
| SCHEMBL1852522 | 0.85 | TRPM8 (0.43) | SMN1; SMN2MEN1KMT2ASERPINE1PTGES | |
| SCHEMBL4016855 | 0.84 | MEN1 (0.41) | SMN1; SMN2MEN1TSHRHTTKMT2A | |
| SCHEMBL1853216 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1TSHRHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090018169-A1 | Sulfonamide Derivatives for the Treatment of Bacterial Infections | LABORATOIRES SERONO SA (CH) | 2009-01-15 | — | — | US | claimed |
| US-20090018169-A1 | Sulfonamide Derivatives for the Treatment of Bacterial Infections | LABORATOIRES SERONO SA (CH) | 2009-01-15 | — | — | US | disclosed |
| US-20090018169-A1 | Sulfonamide Derivatives for the Treatment of Bacterial Infections | LABORATOIRES SERONO SA (CH) | 2009-01-15 | — | — | US | disclosed |
| US-20090018169-A1 | Sulfonamide Derivatives for the Treatment of Bacterial Infections | LABORATOIRES SERONO SA (CH) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018169-A1 | Sulfonamide Derivatives for the Treatment of Bacterial Infections | STS, TST, SULT1A1 | SMN1; SMN2 2147/4885MEN1 2947/4885TSHR 1632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.