Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
| ▸ | IDH2 | P48735 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4717989 | 1.00 | MEN1 (0.47) | MEN1KMT2ATSHRHTTSMN1; SMN2 | |
| SCHEMBL1852234 | 0.88 | HTT (0.51) | MEN1KMT2ATSHRHTTSMN1; SMN2 | |
| SCHEMBL4714646 | 0.86 | TSHR (0.47) | MEN1KMT2ATSHRHTTSMN1; SMN2 | |
| SCHEMBL4717987 | 0.86 | TSHR (0.47) | MEN1KMT2ATSHRHTTSMN1; SMN2 | |
| SCHEMBL1856043 | 0.84 | SMN1; SMN2 (0.56) | MEN1KMT2ATSHRHTTSMN1; SMN2 | |
| SCHEMBL4711910 | 0.84 | MAPT (0.40) | SCN8ATRPV1TRPV4POLBMAPT | |
| SCHEMBL1854854 | 0.83 | SMN1; SMN2 (0.42) | MEN1KMT2ATSHRHTTSMN1; SMN2 | |
| SCHEMBL4016045 | 0.83 | SMN1; SMN2 (0.42) | MEN1KMT2ATSHRHTTSMN1; SMN2 | |
| SCHEMBL5047441 | 0.82 | BCHE (0.44) | MEN1KMT2ATRPV1POLBMAPT | |
| SCHEMBL5040032 | 0.81 | ERBB2 (0.42) | MEN1KMT2ATSHRHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986637-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | Laboratoires Serono SA (CH) | 2008-11-05 | — | — | EP | claimed |
| WO-2007093557-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | LABORATOIRES SERONO S.A. (CH) | 2007-08-23 | — | — | WO | claimed |