Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.45 |
| ▸ | ACACB | O00763 | 2/20 | 0.43 |
| ▸ | ACACA | Q13085 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3129071 | 0.91 | OXTR (0.41) | ACACBACACAOPRM1OPRD1OXTR | |
| SCHEMBL4714704 | 0.74 | ACACB (0.47) | FFAR1FFAR4ACACBACACAOPRM1 | |
| SCHEMBL3142882 | 0.69 | FFAR1 (0.48) | FFAR1FFAR4 | |
| SCHEMBL3143620 | 0.67 | FFAR1 (0.43) | FFAR1FFAR4 | |
| SCHEMBL1747433 | 0.67 | FFAR1 (0.94) | FFAR1FFAR4 | |
| SCHEMBL7417057 | 0.66 | LTA4H (0.46) | FFAR1FFAR4 | |
| SCHEMBL550514 | 0.66 | MEN1 (0.47) | OXTR | |
| SCHEMBL3134853 | 0.65 | NPC1 (0.48) | ACACBACACAOPRM1OPRD1OPRK1 | |
| Benzyloxyphenylpropanoic Acid SCHEMBL1134648 | 0.65 | FFAR1 (1.00) | FFAR1FFAR4 | |
| SCHEMBL1744939 | 0.65 | FFAR1 (1.00) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957073-A2 | MEDICINAL DRUG | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007066784-A2 | DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-06-14 | — | — | WO | disclosed |