Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 12/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | PARG | Q86W56 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyric Acid SCHEMBL4166193 | 0.92 | SLC6A2 (0.48) | SLC6A2SLC6A4KCNH2RXFP1SLC6A3 | |
| Butyric Acid SCHEMBL4157864 | 0.92 | SLC6A2 (0.48) | SLC6A2SLC6A4KCNH2RXFP1SLC6A3 | |
| SCHEMBL4717249 | 0.83 | MAPT (0.44) | SLC6A2SLC6A4KCNH2RXFP1SLC6A3 | |
| SCHEMBL3247263 | 0.81 | SLC6A2 (0.49) | SLC6A2SLC6A4KCNH2RXFP1HTT | |
| SCHEMBL3247259 | 0.81 | SLC6A2 (0.49) | SLC6A2SLC6A4KCNH2RXFP1HTT | |
| Butyric Acid SCHEMBL4159473 | 0.79 | RXFP1 (0.40) | SLC6A2SLC6A4KCNH2RXFP1SLC6A3 | |
| SCHEMBL4717207 | 0.78 | MAPT (0.47) | SLC6A2SLC6A4RXFP1PARGKDM4E | |
| Butyric Acid SCHEMBL4159661 | 0.78 | RXFP1 (0.38) | SLC6A2RXFP1HTTTDP1KDM4E | |
| Butyric Acid SCHEMBL4161016 | 0.78 | RXFP1 (0.38) | SLC6A2RXFP1HTTTDP1KDM4E | |
| SCHEMBL4717707 | 0.78 | RXFP1 (0.40) | RXFP1PARGKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899335-A1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PIERRE FABRE MEDICAMENT (FR) | 2008-03-19 | — | — | EP | claimed |
| WO-2007003611-A1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PIERRE FABRE MEDICAMENT (FR) | 2007-01-11 | — | — | WO | claimed |