Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | PARG | Q86W56 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 5/20 | 0.39 |
| ▸ | HTR2C | P28335 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4717249 | 0.93 | MAPT (0.44) | MAPTRXFP1PARGL3MBTL1PKM | |
| Butyric Acid SCHEMBL4166911 | 0.90 | RXFP1 (0.43) | MAPTRXFP1PARGL3MBTL1PKM | |
| SCHEMBL4712743 | 0.87 | MAPT (0.38) | MAPTRXFP1PARGL3MBTL1PKM | |
| Butyric Acid SCHEMBL4159473 | 0.85 | RXFP1 (0.40) | MAPTRXFP1PARGL3MBTL1GAA | |
| Butyric Acid SCHEMBL4157862 | 0.84 | RXFP1 (0.40) | MAPTRXFP1PARGL3MBTL1GAA | |
| Butyric Acid SCHEMBL4155204 | 0.84 | RXFP1 (0.40) | MAPTRXFP1PARGL3MBTL1GAA | |
| SCHEMBL4717707 | 0.81 | RXFP1 (0.40) | MAPTRXFP1PARGALDH1A1KDM4E | |
| SCHEMBL4717705 | 0.81 | RXFP1 (0.40) | MAPTRXFP1PARGALDH1A1KDM4E | |
| SCHEMBL4716505 | 0.79 | RXFP1 (0.38) | MAPTRXFP1PARGALDH1A1LMNA | |
| SCHEMBL4714713 | 0.78 | SLC6A2 (0.55) | MAPTRXFP1PARGALDH1A1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899335-A1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PIERRE FABRE MEDICAMENT (FR) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007003611-A1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PIERRE FABRE MEDICAMENT (FR) | 2007-01-11 | — | — | WO | disclosed |