Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PARG | Q86W56 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4717207 | 0.93 | MAPT (0.47) | MAPTSLC6A2SLC6A4RXFP1PARG | |
| Butyric Acid SCHEMBL4159473 | 0.91 | RXFP1 (0.40) | MAPTSLC6A2SLC6A4RXFP1PARG | |
| Butyric Acid SCHEMBL4166911 | 0.84 | RXFP1 (0.43) | MAPTRXFP1PARGL3MBTL1PKM | |
| SCHEMBL4714713 | 0.83 | SLC6A2 (0.55) | MAPTSLC6A2SLC6A4RXFP1PARG | |
| SCHEMBL4712743 | 0.81 | MAPT (0.38) | MAPTRXFP1PARGL3MBTL1PKM | |
| SCHEMBL4713516 | 0.81 | RXFP1 (0.34) | SLC6A2SLC6A4RXFP1PARGSLC6A3 | |
| Butyric Acid SCHEMBL4155204 | 0.80 | RXFP1 (0.40) | MAPTRXFP1PARGL3MBTL1GAA | |
| Butyric Acid SCHEMBL4157862 | 0.80 | RXFP1 (0.40) | MAPTRXFP1PARGL3MBTL1GAA | |
| SCHEMBL3247121 | 0.79 | GAA (0.44) | MAPTSLC6A2SLC6A4RXFP1L3MBTL1 | |
| Butyric Acid SCHEMBL4166193 | 0.77 | SLC6A2 (0.48) | MAPTSLC6A2SLC6A4RXFP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899335-A1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PIERRE FABRE MEDICAMENT (FR) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007003611-A1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PIERRE FABRE MEDICAMENT (FR) | 2007-01-11 | — | — | WO | disclosed |