Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7555391 | 0.87 | KCNH2 (0.46) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4714017 | 0.87 | KCNH2 (0.53) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4564657 | 0.87 | KCNH2 (0.53) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4714018 | 0.87 | KCNH2 (0.53) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4714850 | 0.87 | KCNH2 (0.40) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4713107 | 0.81 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL4509604 | 0.78 | TOP2A (0.34) | KCNH2 | |
| SCHEMBL4517645 | 0.78 | KCNH2 (0.39) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4517639 | 0.78 | KCNH2 (0.39) | KCNH2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7555397 | 0.76 | KCNH2 (0.46) | KCNH2SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255739-B1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER LAMBERT CO (US) | 2008-06-11 | — | — | EP | disclosed |