Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 16/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4558292 | 0.98 | ADRB2 (0.45) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| SCHEMBL12119358 | 0.81 | ADRB2 (0.54) | ADRB2ADRB1DRD3 | |
| SCHEMBL4740762 | 0.80 | ADRB2 (0.52) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| SCHEMBL4555603 | 0.80 | ADRB2 (0.49) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| Hydrochloric Acid SCHEMBL1179939 | 0.79 | ADRB2 (0.51) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| Bromide SCHEMBL1683003 | 0.79 | ADRB2 (0.51) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| SCHEMBL1803587 | 0.78 | ADRB2 (0.51) | ADRB2ADRB1DRD3 | |
| SCHEMBL14291843 | 0.77 | ADRB2 (0.52) | ADRB2ADRB1DRD3 | |
| SCHEMBL7840281 | 0.77 | ADRB2 (0.47) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| SCHEMBL4788200 | 0.77 | ADRB2 (0.47) | ADRB2ADRB1ABCB11DRD2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996566-A1 | BEZOTHIAZOL DERIVATIVES AS BETA2 ADRENORECEPTOR AGONISTS | AstraZeneca AB (SE) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007106016-A1 | BEZOTHIAZOL DERIVATIVES AS BETA2 ADRENORECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2007-09-20 | — | — | WO | disclosed |