Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 15/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13225820 | 0.83 | CYP1A2 (0.44) | ADRB2ADRB1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL12119358 | 0.82 | ADRB2 (0.54) | ADRB2ADRB1 | |
| SCHEMBL4555603 | 0.81 | ADRB2 (0.49) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| SCHEMBL4440137 | 0.79 | ADRB2 (0.56) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| Acetic Acid SCHEMBL4742751 | 0.79 | ADRB2 (0.47) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| SCHEMBL14291843 | 0.78 | ADRB2 (0.52) | ADRB2ADRB1 | |
| SCHEMBL4740762 | 0.78 | ADRB2 (0.52) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| SCHEMBL4788200 | 0.78 | ADRB2 (0.47) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| Bromide SCHEMBL1683003 | 0.77 | ADRB2 (0.51) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| SCHEMBL4715369 | 0.77 | ADRB2 (0.46) | ADRB2ADRB1ABCB11DRD2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558677-B1 | BIOLOGICALLY ACTIVE AMINES | ASTRAZENECA AB (SE) | 2001-08-16 | — | — | EP | disclosed |
| US-5763465-A | 7-(2-aminoethyl) benzothiazolones | ASTRA PHARMACEUTICALS LIMITED (GB) | 1998-06-09 | — | — | US | disclosed |
| US-5648370-A | 7-(2-aminoethyl) benzothiazolones | ASTRA PHARMACEUTICALS LIMITED (GB) | 1997-07-15 | — | — | US | disclosed |
| WO-1993023385-A1 | BIOLOGICALLY ACTIVE AMINES | FISONS PLC (GB) | 1993-11-25 | — | — | WO | disclosed |
| EP-0558677-A1 | BIOLOGICALLY ACTIVE AMINES | Astra Pharmaceuticals Limited (GB) | 1993-09-08 | — | — | EP | disclosed |
| WO-1992008708-A1 | BIOLOGICALLY ACTIVE AMINES | FISONS PLC (GB) | 1992-05-29 | — | — | WO | disclosed |