Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 14/20 | 0.34 |
| ▸ | PARG | Q86W56 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR1F | P30939 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyric Acid SCHEMBL4166218 | 0.92 | KDM4E (0.36) | RXFP1HTR6BRD4KDM4EHSD17B10 | |
| Butyric Acid SCHEMBL4155631 | 0.91 | KDM4E (0.35) | RXFP1HTR6KDM4EHSD17B10MAPT | |
| Butyric Acid SCHEMBL4153181 | 0.91 | KDM4E (0.35) | RXFP1HTR6KDM4EHSD17B10MAPT | |
| SCHEMBL3244781 | 0.82 | LMNA (0.37) | HTR6KDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL3244775 | 0.82 | LMNA (0.37) | HTR6KDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL3245506 | 0.82 | LMNA (0.37) | HTR6KDM4EALDH1A1HSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL3250783 | 0.81 | LMNA (0.37) | HTR6KDM4EALDH1A1HSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL3249868 | 0.81 | LMNA (0.37) | HTR6KDM4EALDH1A1HSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL3249873 | 0.81 | LMNA (0.37) | HTR6KDM4EALDH1A1HSD17B10MAPT | |
| Butyric Acid SCHEMBL4162712 | 0.79 | RXFP1 (0.35) | RXFP1HTR6KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899335-A1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PIERRE FABRE MEDICAMENT (FR) | 2008-03-19 | — | — | EP | claimed |
| WO-2007003611-A1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PIERRE FABRE MEDICAMENT (FR) | 2007-01-11 | — | — | WO | claimed |