Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylmethane SCHEMBL2494259 | 0.87 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2SLC1A1CYP1A2 | |
| Benzyl Alcohol SCHEMBL18953109 | 0.86 | TSHR (0.58) | SLC7A5SLC1A3SLC1A2SLC1A1TSHR | |
| Valine SCHEMBL27680015 | 0.85 | SLC7A5 (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1TSHR | |
| Valine SCHEMBL4726209 | 0.85 | SLC7A5 (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1TSHR | |
| Valine SCHEMBL11201581 | 0.84 | SLC7A5 (0.54) | SLC7A5SLC1A3SLC1A2SLC1A1TSHR | |
| Phenylacetic Acid SCHEMBL8902802 | 0.84 | AKR1B1 (0.61) | SLC7A5SLC1A3SLC1A2SLC1A1TSHR | |
| Benzyl Bromide SCHEMBL8876464 | 0.84 | SLC7A5 (0.54) | SLC7A5SLC1A3SLC1A2SLC1A1TSHR | |
| Benzyl Alcohol SCHEMBL15655796 | 0.83 | TSHR (0.54) | SLC7A5SLC1A3SLC1A2SLC1A1TSHR | |
| Hydrocinnamyl Alcohol SCHEMBL28329674 | 0.83 | SLC7A5 (0.48) | SLC7A5SLC1A3SLC1A2SLC1A1CYP1A2 | |
| Phenylalanine SCHEMBL531086 | 0.82 | SLC7A5 (0.76) | SLC7A5SLC1A3SLC1A2SLC1A1ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615904-B1 | SUBSTITUTED BENZOSULPHONAMIDES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ASTRAZENECA AB (SE) | 2008-02-27 | — | — | EP | disclosed |
| US-20070021606-A1 | Therapeutic compounds | ASTRAZENECA AB (SE) | 2007-01-25 | — | — | US | disclosed |
| EP-1615904-A2 | SUBSTITUTED BENZOSULPHONAMIDE AS POTENTIATORS OF GLUTAMATE RECEPTORS | AstraZeneca AB (SE) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004092135-A2 | SUBSTITUTED BENZOSULPHONAMIDE AS POTENTIATORS OF GLUTAMATE RECEPTORS | ASTRAZENECA (SE) | 2004-10-28 | — | — | WO | disclosed |
| US-5011927-A | Preparation of 2-amino-4-fluoropyrimidine derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1991-04-30 | — | — | US | disclosed |
| US-4267388-A | BY SULFONATING A BENZYL ALCOHOL COMPOUND, REDUCING THE SULFONYL DERIVATIVE TO A HALOSTYRENYL COMPOUND, AND DEHYDROHALOGENATING TO THE ETHYNYLBENZENE | WILLIAM H. RORER, INC. (US) | 1981-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021606-A1 | Therapeutic compounds | GRIN1, GRIN3A, GRM2 | SLC7A5 836/4885SLC1A3 54/4885SLC1A2 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.