Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.56 |
| ▸ | SLC1A1 | P43005 | 6/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL27680015 | 1.00 | SLC7A5 (0.56) | SLC7A5SLC1A1SLC1A3SLC1A2LOXL2 | |
| Valine SCHEMBL15657599 | 0.93 | SLC7A5 (0.52) | SLC7A5SLC1A1SLC1A3SLC1A2LOXL2 | |
| Diphenylmethane SCHEMBL2494259 | 0.87 | SLC7A5 (0.58) | SLC7A5SLC1A1SLC1A3SLC1A2CYP1A2 | |
| Benzylamine SCHEMBL15657392 | 0.86 | LOXL2 (0.58) | SLC7A5SLC1A1SLC1A3SLC1A2LOXL2 | |
| Valine SCHEMBL4716541 | 0.85 | SLC7A5 (0.56) | SLC7A5SLC1A1SLC1A3SLC1A2CYP1A2 | |
| Phenylacetic Acid SCHEMBL8902802 | 0.84 | AKR1B1 (0.61) | SLC7A5SLC1A1SLC1A3SLC1A2CYP1A2 | |
| Valine SCHEMBL11201581 | 0.84 | SLC7A5 (0.54) | SLC7A5SLC1A1SLC1A3SLC1A2CYP1A2 | |
| Benzyl Bromide SCHEMBL8876464 | 0.84 | SLC7A5 (0.54) | SLC7A5SLC1A1SLC1A3SLC1A2CYP1A2 | |
| Phenylalanine SCHEMBL531086 | 0.82 | SLC7A5 (0.76) | SLC7A5SLC1A1SLC1A3SLC1A2ALPI | |
| Phenylalanine SCHEMBL8595582 | 0.82 | SLC7A5 (0.76) | SLC7A5SLC1A1SLC1A3SLC1A2ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080009534-A1 | SUBSTITUTED ACID DERIVATIVES USEFUL AS ANTIDIABETIC AND ANTIOBESITY AGENTS AND METHOD | BRISTOL-MYERS SQUIBB COMPANY | 2008-01-10 | — | — | US | disclosed |
| WO-2008006044-A2 | SUBSTITUTED ACID DERIVATIVES USEFUL AS ANTIDIABETIC AND ANTIOBESITY AGENTS AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-01-10 | — | — | WO | disclosed |
| EP-0874863-A1 | 3-DEOXY-3-DESCLADINOSE DERIVATIVES OF ERYTHROMYCINS A AND B | ABBOTT LABORATORIES (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997017357-A1 | 3-DEOXY-3-DESCLADINOSE DERIVATIVES OF ERYTHROMYCINS A AND B | ABBOTT LABORATORIES (US) | 1997-05-15 | — | — | WO | disclosed |
| CN-1110502-A | Herbicidal compounds | SHELL INT RESEARCH (NL) | 1995-10-25 | — | — | CN | disclosed |
| CN-1029959-C | Process for preparing herbicidal compounds | SHELL INT RESEARCH (NL) | 1995-10-11 | — | — | CN | disclosed |
| EP-0467473-B1 | Herbicidal compounds | SHELL INT RESEARCH (NL) | 1994-10-05 | — | — | EP | disclosed |
| US-5304532-A | For preemergence or postemergence use | SHELL RESEARCH LIMITED | 1994-04-19 | — | — | US | disclosed |
| CN-1060090-A | HERBICIDAL COMPOUNDS | SHELL INT RESEARCH (NL) | 1992-04-08 | — | — | CN | disclosed |
| EP-0467473-A1 | Herbicidal compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-01-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009534-A1 | SUBSTITUTED ACID DERIVATIVES USEFUL AS ANTIDIABETIC AND ANTIOBESITY AGENTS AND METHOD | GPR119, LIPC, CEL | SLC7A5 925/4885SLC1A1 2065/4885SLC1A3 1661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.