Valine

Valine

SCHEMBL11201581

CC(C)[C@H](N)C(=O)O.O=C(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.54

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.54
SLC1A3 P43003 4/20 0.51
SLC1A2 P43004 4/20 0.51
SLC1A1 P43005 4/20 0.51
MEN1 O00255 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
KMT2A Q03164 1/20 0.47
TSHR P16473 1/20 0.47
ALPI P09923 1/20 0.47
PKM P14618 1/20 0.47
PTGS1 P23219 1/20 0.47
XIAP P98170 1/20 0.47
SLC15A1 P46059 1/20 0.47
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
AKR1B1 P15121 1/20 0.45
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylacetic Acid SCHEMBL8902802 0.89 AKR1B1 (0.61) SLC7A5SLC1A3SLC1A2SLC1A1MEN1
Valine SCHEMBL7645312 0.86 SLC7A5 (0.50) SLC7A5SLC1A3SLC1A2SLC1A1MEN1
Diphenylmethane SCHEMBL2494259 0.85 SLC7A5 (0.58) SLC7A5SLC1A3SLC1A2SLC1A1MEN1
Valine SCHEMBL27680015 0.84 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2SLC1A1MEN1
Valine SCHEMBL4726209 0.84 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2SLC1A1MEN1
Valine SCHEMBL4716541 0.84 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2SLC1A1MEN1
Benzyl Bromide SCHEMBL8876464 0.82 SLC7A5 (0.54) SLC7A5SLC1A3SLC1A2SLC1A1MEN1
Dl-Phenylalanine SCHEMBL6237224 0.81 SLC7A5 (0.76) SLC7A5SLC1A3SLC1A2SLC1A1ALPI
Phenylalanine SCHEMBL8595582 0.81 SLC7A5 (0.76) SLC7A5SLC1A3SLC1A2SLC1A1ALPI
Phenylalanine SCHEMBL531086 0.81 SLC7A5 (0.76) SLC7A5SLC1A3SLC1A2SLC1A1ALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4380619-A POLYBENZOTHIAZOLES; N-HETEROCYCLIC POLYMERS; SOLUBILITY; HEAT RESISTANCE; AIRCRAFT; AEROSPACE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1983-04-19 US disclosed