Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CTSA | P10619 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 2/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23554436 | 0.70 | ALDH1A1 (0.41) | POLA1CDK2CTSAALDH1A1KDM4E | |
| SCHEMBL1998243 | 0.68 | ALDH1A1 (0.37) | POLA1CDK2CTSAALDH1A1KDM4E | |
| SCHEMBL4718044 | 0.67 | MTNR1A (0.34) | — | |
| SCHEMBL4718040 | 0.66 | CYP2C9 (0.45) | — | |
| SCHEMBL5255150 | 0.65 | HRH3 (0.51) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL19629639 | 0.65 | KDM4E (0.37) | POLA1CDK2CTSAALDH1A1KDM4E | |
| SCHEMBL18937619 | 0.65 | ALDH1A1 (0.37) | POLA1CDK2CTSAALDH1A1KDM4E | |
| SCHEMBL8479069 | 0.64 | ITGAV (0.57) | — | |
| SCHEMBL2008297 | 0.63 | ALDH1A1 (0.44) | CDK2CTSAALDH1A1KDM4EMAPK14 | |
| SCHEMBL2188616 | 0.62 | CTNNB1 (0.47) | CDK2CTSAALDH1A1KDM4EMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216230-B1 | FUSED CYCLOHEPTANE AND FUSED AZACYCLOHEPTANE COMPOUNDS AND THEIR USE AS INTEGRIN RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2008-04-23 | — | — | EP | disclosed |