Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | TOP2A | P11388 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.62 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.62 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.62 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15281384 | 0.92 | KDM4E (0.65) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL4718945 | 0.90 | PIK3CG (0.71) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL15281352 | 0.88 | KDM4E (0.62) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL15281357 | 0.88 | KDM4E (0.70) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8924883 | 0.86 | KDM4E (0.75) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL15281380 | 0.86 | KDM4E (0.62) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10920123 | 0.86 | KDM4E (0.72) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8924080 | 0.85 | KDM4E (0.80) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8192604 | 0.84 | KDM4E (0.78) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL4717938 | 0.82 | PIK3CG (0.72) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230235-B1 | COMPOUNDS WITH ANTIBACTERIAL AND ANTIPARASITIC PROPERTIES | NEW PHARMA RES SWEDEN AB (SE) | 2008-06-11 | — | — | EP | disclosed |
| US-6967205-B1 | Compounds with antibacterial and antiparasitic properties | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2005-11-22 | — | — | US | disclosed |