Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.78 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | TOP2A | P11388 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.66 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.66 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.66 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10807306 | 0.92 | KDM4E (0.81) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8924080 | 0.91 | KDM4E (0.80) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8924883 | 0.90 | KDM4E (0.75) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL29350842 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10809240 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL19122738 | 0.88 | KDM4E (0.77) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL5570774 | 0.88 | KDM4E (0.77) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8924402 | 0.87 | ALDH1A1 (0.77) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10807699 | 0.87 | KDM4E (0.77) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10374013 | 0.86 | KDM4E (0.79) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10202631-B2 | Multi-tiered, high through-put screen for compounds effective against bacterial biofilm compounds effective for inhibiting and eradicating bacterial biofilm | UNIVERSITY OF CINCINNATI (US) | 2019-02-12 | — | — | US | claimed |
| US-10704076-B2 | Multi-tiered high through-put screen for compounds effective against bacterial biofilm and compounds effective for inhibiting and eradicating bacterial biofilm | UNIVERSITY OF CINCINNATI (US) | 2020-07-07 | — | — | US | disclosed |
| US-20190127776-A1 | MULTI-TIERED HIGH THROUGH-PUT SCREEN FOR COMPOUNDS EFFECTIVE AGAINST BACTERIAL BIOFILM AND COMPOUNDS EFFECTIVE FOR INHIBITING AND ERADICATING BACTERIAL BIOFILM | UNIVERSITY OF CINCINNATI (US) | 2019-05-02 | — | — | US | disclosed |
| US-10202631-B2 | Multi-tiered, high through-put screen for compounds effective against bacterial biofilm compounds effective for inhibiting and eradicating bacterial biofilm | UNIVERSITY OF CINCINNATI (US) | 2019-02-12 | — | — | US | disclosed |
| US-20160024551-A1 | MULTI-TIERED, HIGH THROUGH-PUT SCREEN FOR COMPOUNDS EFFECTIVE AGAINST BACTERIAL BIOFILM COMPOUNDS EFFECTIVE FOR INHIBITING AND ERADICATING BACTERIAL BIOFILM | UNIVERSITY OF CINCINNATI (US) | 2016-01-28 | — | — | US | disclosed |
| US-20160024551-A1 | MULTI-TIERED, HIGH THROUGH-PUT SCREEN FOR COMPOUNDS EFFECTIVE AGAINST BACTERIAL BIOFILM COMPOUNDS EFFECTIVE FOR INHIBITING AND ERADICATING BACTERIAL BIOFILM | UNIVERSITY OF CINCINNATI (US) | 2016-01-28 | — | — | US | disclosed |
| WO-2014152895-A1 | MULTI-TIERED HIGH THROUGH-PUT SCREEN FOR COMPOUNDS EFFECTIVE AGAINST BACTERIAL BIOFILM AND COMPOUNDS EFFECTIVE FOR INHIBITING AND ERADICATING BACTERIAL BIOFILM | UNIVERSITY OF CINCINNATI (US) | 2014-09-25 | — | — | WO | disclosed |
| WO-2014152895-A1 | MULTI-TIERED HIGH THROUGH-PUT SCREEN FOR COMPOUNDS EFFECTIVE AGAINST BACTERIAL BIOFILM AND COMPOUNDS EFFECTIVE FOR INHIBITING AND ERADICATING BACTERIAL BIOFILM | UNIVERSITY OF CINCINNATI (US) | 2014-09-25 | — | — | WO | disclosed |
| EP-0997466-A1 | Novel antimicrobial lactam-quinolones | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 2000-05-03 | — | — | EP | disclosed |
| US-5656623-A | BACTERICIDES; ANTIBIOTICS | THE PROCTER & GAMBLE COMPANY (US) | 1997-08-12 | — | — | US | disclosed |
| US-5648346-A | Antimicrobial carbacephem-quinolones | THE PROCTER & GAMBLE COMPANY (US) | 1997-07-15 | — | — | US | disclosed |
| US-5646139-A | TREATING AND PREVENTING INFECTION | THE PROCTER & GAMBLE COMPANY (US) | 1997-07-08 | — | — | US | disclosed |
| US-5637580-A | ANTIBIOTICS | THE PROCTER & GAMBLE COMPANY (US) | 1997-06-10 | — | — | US | disclosed |
| US-5631256-A | IMPROVED POTENCY, BROADER SPECTRUM | THE PROCTER & GAMBLE COMPANY (US) | 1997-05-20 | — | — | US | disclosed |
| US-5328908-A | Antimicrobial quinolone thioureas | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1994-07-12 | — | — | US | disclosed |
| WO-1991016310-A1 | ANTIMICROBIAL QUINOLONE THIOUREAS | NORWICH-EATON PHARMACEUTICALS, INC. (US) | 1991-10-31 | — | — | WO | disclosed |
| EP-0366189-A2 | Novel antimicrobial lactam-quinolones | Norwich Eaton Pharmaceuticals, Inc. (US) | 1990-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024551-A1 | MULTI-TIERED, HIGH THROUGH-PUT SCREEN FOR COMPOUNDS EFFECTIVE AGAINST BACTERIAL BIOFILM COMPOUNDS EFFECTIVE FOR INHIBITING AND ERADICATING BACTERIAL BIOFILM | PGLS, GLO1, FDPS | KDM4E 381/4885ALDH1A1 453/4885LMNA 3556/4885 |
| US-20190127776-A1 | MULTI-TIERED HIGH THROUGH-PUT SCREEN FOR COMPOUNDS EFFECTIVE AGAINST BACTERIAL BIOFILM AND COMPOUNDS EFFECTIVE FOR INHIBITING AND ERADICATING BACTERIAL BIOFILM | ABCG2, TOE1, TFPI | KDM4E 1064/4885ALDH1A1 204/4885LMNA 3709/4885 |
| US-10202631-B2 | Multi-tiered, high through-put screen for compounds effective against bacterial biofilm compounds effective for inhibiting and eradicating bacterial biofilm | PGLS, GLO1, FDPS | KDM4E 381/4885ALDH1A1 453/4885LMNA 3556/4885 |
| US-10704076-B2 | Multi-tiered high through-put screen for compounds effective against bacterial biofilm and compounds effective for inhibiting and eradicating bacterial biofilm | ABCG2, TOE1, TFPI | KDM4E 1064/4885ALDH1A1 204/4885LMNA 3709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.