Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GLP1R | P43220 | 1/20 | 0.32 |
| ▸ | LATS1 | O95835 | 3/20 | 0.31 |
| ▸ | LATS2 | Q9NRM7 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4720835 | 0.83 | TP53 (0.31) | TP53 | |
| SCHEMBL4716898 | 0.80 | TP53 (0.32) | TP53 | |
| SCHEMBL14086452 | 0.79 | CXCR2 (0.35) | TP53LMNAGAAHTTGLP1R | |
| SCHEMBL4718820 | 0.76 | — | — | |
| SCHEMBL5751959 | 0.74 | ACLY (0.30) | — | |
| SCHEMBL12660311 | 0.72 | MAPK14 (0.35) | LMNAHTT | |
| SCHEMBL1882670 | 0.70 | MAPK14 (0.39) | — | |
| SCHEMBL14086466 | 0.70 | GLP1R (0.37) | GLP1RLATS1LATS2 | |
| SCHEMBL5748131 | 0.67 | CDC7 (0.34) | LMNA | |
| SCHEMBL14086454 | 0.67 | CXCR2 (0.33) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287472-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-20 | — | — | US | disclosed |
| US-20080287472-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-20 | — | — | US | disclosed |
| US-20080287472-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-20 | — | — | US | disclosed |
| EP-1575949-B1 | FUNGICIDES | SYNGENTA LTD (GB) | 2008-04-02 | — | — | EP | disclosed |
| EP-1575949-B1 | FUNGICIDES | SYNGENTA LTD (GB) | 2008-04-02 | — | — | EP | disclosed |
| US-20070066605-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. | 2007-03-22 | — | — | US | disclosed |
| US-20070066605-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. | 2007-03-22 | — | — | US | disclosed |
| US-20070066605-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. | 2007-03-22 | — | — | US | disclosed |
| EP-1575949-A1 | FUNGICIDES | Syngenta Limited (GB) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004056826-A1 | FUNGICIDES | SYNGENTA LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287472-A1 | Fungicides | PNPO, CYP4X1, CYP1A2 | TP53 3375/4885LMNA 3502/4885GAA 496/4885 |
| US-20070066605-A1 | Fungicides | CYP4X1, CYP4F8, CBR3 | TP53 4668/4885LMNA 1745/4885GAA 3912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.