Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4716898 | 0.89 | TP53 (0.32) | TP53 | |
| SCHEMBL4718003 | 0.83 | TP53 (0.35) | TP53 | |
| SCHEMBL13906839 | 0.79 | MAPK14 (0.32) | — | |
| SCHEMBL4718820 | 0.76 | — | — | |
| SCHEMBL1886846 | 0.72 | MAPK14 (0.31) | — | |
| SCHEMBL1887676 | 0.70 | MAPK14 (0.39) | — | |
| SCHEMBL4718007 | 0.70 | CSNK2A1 (0.32) | — | |
| SCHEMBL7831913 | 0.70 | CRHR1 (0.36) | TP53 | |
| SCHEMBL4916811 | 0.70 | CXCR2 (0.30) | — | |
| SCHEMBL13906899 | 0.70 | MAPK14 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287472-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-20 | — | — | US | disclosed |
| US-20080287472-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-20 | — | — | US | disclosed |
| US-20080287472-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-20 | — | — | US | disclosed |
| EP-1575949-B1 | FUNGICIDES | SYNGENTA LTD (GB) | 2008-04-02 | — | — | EP | disclosed |
| EP-1575949-B1 | FUNGICIDES | SYNGENTA LTD (GB) | 2008-04-02 | — | — | EP | disclosed |
| US-20070066605-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. | 2007-03-22 | — | — | US | disclosed |
| US-20070066605-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. | 2007-03-22 | — | — | US | disclosed |
| US-20070066605-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. | 2007-03-22 | — | — | US | disclosed |
| EP-1575949-A1 | FUNGICIDES | Syngenta Limited (GB) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004056826-A1 | FUNGICIDES | SYNGENTA LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287472-A1 | Fungicides | PNPO, CYP4X1, CYP1A2 | TP53 3375/4885 |
| US-20070066605-A1 | Fungicides | CYP4X1, CYP4F8, CBR3 | TP53 4668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.