Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 12/20 | 0.42 |
| ▸ | RAF1 | P04049 | 4/20 | 0.41 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.38 |
| ▸ | SLC34A3 | Q8N130 | 1/20 | 0.38 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15420997 | 1.00 | SLC34A2 (0.42) | SLC34A2RAF1SLC34A1SLC34A3SLC20A1 | |
| SCHEMBL15420982 | 0.93 | SLC34A2 (0.43) | SLC34A2RAF1SLC34A1SLC34A3SLC20A1 | |
| SCHEMBL46916 | 0.93 | SLC34A2 (0.43) | SLC34A2RAF1SLC34A1SLC34A3SLC20A1 | |
| SCHEMBL46594 | 0.91 | SLC34A2 (0.40) | SLC34A2RAF1SLC34A1SLC34A3SLC20A1 | |
| SCHEMBL15420883 | 0.91 | SLC34A2 (0.40) | SLC34A2RAF1SLC34A1SLC34A3SLC20A1 | |
| SCHEMBL15420885 | 0.91 | SLC34A2 (0.40) | SLC34A2RAF1SLC34A1SLC34A3SLC20A1 | |
| SCHEMBL41238 | 0.88 | SLC34A2 (0.45) | SLC34A2RAF1SLC34A1SLC34A3SLC20A1 | |
| SCHEMBL41236 | 0.88 | SLC34A2 (0.45) | SLC34A2RAF1SLC34A1SLC34A3SLC20A1 | |
| SCHEMBL46950 | 0.87 | RAF1 (0.49) | SLC34A2RAF1CYP3A4CYP2C9 | |
| SCHEMBL15420678 | 0.87 | SLC34A2 (0.47) | SLC34A2RAF1SLC34A1SLC34A3SLC20A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2591354-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2016-09-07 | — | — | EP | disclosed |
| EP-2591354-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2016-09-07 | — | — | EP | disclosed |
| US-20140023611-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. | 2014-01-23 | — | — | US | disclosed |
| US-20140023611-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. | 2014-01-23 | — | — | US | disclosed |
| US-20140023611-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. | 2014-01-23 | — | — | US | disclosed |
| WO-2012006475-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2012-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140023611-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | SLC10A2, SLC34A2, SLC34A3 | SLC34A2 2/4885RAF1 3987/4885SLC34A1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.