Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3197320 | 0.90 | IDO1 (0.49) | IDO1ALDH1A1L3MBTL1ADCY10TLR8 | |
| SCHEMBL3210074 | 0.87 | TLR8 (0.41) | ALDH1A1L3MBTL1TLR8CSNK1DPRNP | |
| SCHEMBL3406203 | 0.87 | GAA (0.50) | IDO1ADCY10TLR8PLA2G2ADHFR | |
| SCHEMBL3219290 | 0.86 | PLA2G2A (0.48) | IDO1ADCY10TLR8CSNK1DPLA2G2A | |
| SCHEMBL3214978 | 0.86 | TP53 (0.47) | ALDH1A1L3MBTL1TLR8CSNK1DKDM4E | |
| SCHEMBL3218795 | 0.85 | TLR8 (0.62) | ADCY10TLR8ADORA3ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL3208543 | 0.85 | TP53 (0.46) | ALDH1A1L3MBTL1TLR8CSNK1DKDM4E | |
| SCHEMBL3196286 | 0.84 | TLR8 (0.49) | IDO1ALDH1A1ADCY10TLR8KDM4E | |
| SCHEMBL3210319 | 0.82 | DPP4 (0.39) | TLR8PRNPPLA2G2AKDM4ESMN1; SMN2 | |
| SCHEMBL3220931 | 0.82 | TLR8 (0.43) | IDO1L3MBTL1ADCY10TLR8PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917245-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | Abbott GmbH & Co. KG (DE) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007022946-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | ABBOTT GMBH & CO. KG (DE) | 2007-03-01 | — | — | WO | disclosed |