Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL3195788 | 0.95 | MAPK1 (0.53) | MAPK1ALDH1A1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL4761613 | 0.81 | GRIN2B (0.38) | MAPK1ALDH1A1KMT2ACYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL3211777 | 0.81 | LMNA (0.42) | MAPK1ALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL4715918 | 0.81 | MEN1 (0.42) | MAPK1ALDH1A1KMT2ACYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL3211750 | 0.80 | MEN1 (0.41) | MAPK1ALDH1A1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL4715041 | 0.79 | EGFR (0.39) | MAPK1ALDH1A1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL4717313 | 0.79 | CYP1A2 (0.51) | MAPK1ALDH1A1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL3214830 | 0.79 | GRIN2B (0.40) | MAPK1ALDH1A1KMT2ACYP2D6TDP1 | |
| Hydrochloric Acid SCHEMBL3214937 | 0.79 | EGFR (0.38) | MAPK1ALDH1A1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL4713958 | 0.79 | TLR7 (0.46) | ALDH1A1CYP1A2CYP3A4CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917245-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | Abbott GmbH & Co. KG (DE) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007022946-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | ABBOTT GMBH & CO. KG (DE) | 2007-03-01 | — | — | WO | disclosed |