Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 8/20 | 0.36 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4718551 | 1.00 | P2RX7 (0.36) | P2RX7F10F2TSHRCACNA2D1 | |
| SCHEMBL4720216 | 0.95 | F10 (0.35) | P2RX7F10F2TSHRCXCR3 | |
| SCHEMBL4720220 | 0.95 | F10 (0.35) | P2RX7F10F2TSHRCXCR3 | |
| SCHEMBL4723010 | 0.94 | P2RX7 (0.35) | P2RX7F10F2SOS1ABL1 | |
| SCHEMBL4723006 | 0.94 | P2RX7 (0.35) | P2RX7F10F2SOS1ABL1 | |
| SCHEMBL4720852 | 0.92 | F10 (0.36) | P2RX7F10F2CXCR3ABL1 | |
| SCHEMBL4720844 | 0.92 | F10 (0.36) | P2RX7F10F2CXCR3ABL1 | |
| SCHEMBL4722181 | 0.92 | P2RX7 (0.36) | P2RX7CACNA2D1CACNA2D2SOS1CXCR3 | |
| SCHEMBL4722188 | 0.92 | P2RX7 (0.36) | P2RX7CACNA2D1CACNA2D2SOS1CXCR3 | |
| SCHEMBL4721627 | 0.92 | P2RX7 (0.36) | P2RX7F10F2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |