SCHEMBL471865

SCHEMBL471865

C1CCC(C2=NCCO2)C(C2=NCCO2)C1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 7/20 0.44
ADRA2B P18089 7/20 0.44
ADRA2C P18825 7/20 0.44
ADRA1A P35348 3/20 0.44
GMNN O75496 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
HTR1A P08908 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
TSHR P16473 1/20 0.35
OPRK1 P41145 1/20 0.35
HIF1A Q16665 1/20 0.35
NISCH Q9Y2I1 1/20 0.35
NOS3 P29474 2/20 0.31
NOS1 P29475 2/20 0.31
NOS2 P35228 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11743173 0.90 ADRA2A (0.38) ADRA2AADRA2BADRA2CADRA1AGMNN
SCHEMBL746454 0.84 ADRA2A (0.37) ADRA2AADRA2BADRA2CADRA1AGMNN
SCHEMBL961726 0.81 ADRA2A (0.44) ADRA2AADRA2BADRA2CADRA1AGMNN
SCHEMBL961378 0.79 ADRA2A (0.47) ADRA2AADRA2BADRA2CADRA1AGMNN
Hydrogen Sulfide SCHEMBL721911 0.77 ADRA2A (0.46) ADRA2AADRA2BADRA2CADRA1AGMNN
SCHEMBL11740603 0.76
SCHEMBL19612832 0.75
SCHEMBL2778023 0.75 ADRA2A (0.38) ADRA2AADRA2BADRA2CADRA1AGMNN
SCHEMBL543405 0.74 ADRA2A (0.39) ADRA2AADRA2BADRA2CADRA1AGMNN
SCHEMBL12158794 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070184264-A1 Flame-retardant polyester artificial hair KANEKA CORPORATION (JP) 2007-08-09 US claimed
US-11892104-B2 Flexible tube for endoscopes and method for producing same FUJIFILM CORPORATION (JP) 2024-02-06 US disclosed
WO-2023226835-A1 POLYESTER, AND PREPARATION METHOD THEREFOR AND USE THEREOF 珠海金发生物材料有限公司 2023-11-30 WO disclosed
US-20230340252-A1 RESIN COMPOSITION AND ELECTROMAGNETIC WAVE ABSORBER MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2023-10-26 US disclosed
EP-4261250-A1 RESIN COMPOSITION, PELLET, MOLDED ARTICLE AND METHOD FOR PRODUCING RESIN COMPOSITION Mitsubishi Chemical Corporation (JP) 2023-10-18 EP disclosed
US-20230303826-A1 RESIN COMPOSITION, PELLET AND MOLDED ARTICLE, AND PROCESS FOR PRODUCING RESIN COMPOSITION MITSUBISHI CHEMICAL CORPORATION (JP) 2023-09-28 US disclosed
US-20230242747-A1 RESIN COMPOSITION, FORMED ARTICLE , ELECTROMAGNETIC WAVE ABSORBER, AND METHOD FOR MEASURING ABSORBANCE OF RESIN COMPOSITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2023-08-03 US disclosed
EP-4206257-A1 SEMIAROMATIC POLYESTER, AND PREPARATION METHOD AND APPLICATION THEREOF Jiangsu Kingfa Sci. & Tech. Advanced Materials Co., Ltd. (CN) 2023-07-05 EP disclosed
US-20230139268-A1 FLEXIBLE TUBE FOR ENDOSCOPE, ENDOSCOPIC MEDICAL DEVICE, AND METHODS FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2023-05-04 US disclosed
WO-2023071796-A1 SEMI-AROMATIC POLYESTER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 江苏金发科技新材料有限公司 2023-05-04 WO disclosed
EP-1640406-A1 ALIPHATIC POLYESTER RESIN COMPOSITION, METHOD FOR PRODUCTION THEREOF, MOLDED ARTICLE AND FOAMED ARTICLE COMPRISING THE RESIN COMPOSITION UNITIKA LTD. (JP) 2006-03-29 EP disclosed
US-20040254270-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2004-12-16 US disclosed
US-20040242803-A1 Resin composition and molded article, film, and fiber each comprising the same TORAY INDUSTRIES, INC. (JP) 2004-12-02 US disclosed
EP-1466946-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2004-10-13 EP disclosed
EP-1445282-A1 RESIN COMPOSITION AND MOLDED ARTICLE FILM AND FIBER EACH COMPRISING THE SAME TORAY INDUSTRIES, INC. (JP) 2004-08-11 EP disclosed
US-6740402-B2 HAVING RESISTANCES TO HYDROLYSIS AND FATIGUE FROM FLEXING AT HIGH LEVELS AND USABLE FOR APPLICATIONS OF PAPERMAKING CANVAS, TIRE CORD AND STERILIZED FABRICS TEIJIN LIMITED (JP) 2004-05-25 US disclosed
US-20030143397-A1 Having resistances to hydrolysis and fatigue from flexing at high levels and usable for applications of papermaking canvas, tire cord and sterilized fabrics TEIJIN LIMITED (JP) 2003-07-31 US disclosed
EP-1304402-A1 POLYESTER FIBER TEIJIN LIMITED (JP) 2003-04-23 EP disclosed
EP-0710684-B1 Preparation process of polyhydroxycarboxylic acid MITSUI CHEMICALS INC (JP) 2001-01-31 EP disclosed
EP-0710684-A2 Preparation process of polyhydroxycarboxylic acid MITSUI TOATSU CHEMICALS, Inc. (JP) 1996-05-08 EP disclosed