Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.35 |
| ▸ | F2 | P00734 | 5/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4718916 | 1.00 | F10 (0.35) | F10F2P2RX7CXCR3ACACB | |
| SCHEMBL4721646 | 0.92 | F10 (0.37) | F10F2P2RX7CXCR3 | |
| SCHEMBL4720852 | 0.92 | F10 (0.36) | F10F2P2RX7CXCR3 | |
| SCHEMBL4721640 | 0.92 | F10 (0.37) | F10F2P2RX7CXCR3 | |
| SCHEMBL4720844 | 0.92 | F10 (0.36) | F10F2P2RX7CXCR3 | |
| SCHEMBL4719094 | 0.91 | F10 (0.36) | F10F2P2RX7CXCR3 | |
| SCHEMBL4719096 | 0.91 | F10 (0.36) | F10F2P2RX7CXCR3 | |
| SCHEMBL4721627 | 0.91 | P2RX7 (0.36) | F10F2P2RX7ACACB | |
| SCHEMBL4721632 | 0.91 | P2RX7 (0.36) | F10F2P2RX7ACACB | |
| SCHEMBL4718554 | 0.90 | P2RX7 (0.36) | F10F2P2RX7CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |